E4389

β-Estradiol-Water Soluble

BioReagent, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): Cyclodextrin-encapsulated 17β-estradiol

Select a Size

Pack Size SKU Availability Price
100 MG E4389-100-MG In Stock ₹ 24,994.93

E4389 - 100 MG

₹ 24,994.93

In Stock

Quantity

1

Base Price: ₹ 24,994.93

GST (18%): ₹ 4,499.087

Total Price: ₹ 29,494.017

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

product line

BioReagent

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 25 mg/mL, clear to slightly hazy

shipped in

ambient

storage temp.

room temp

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O.C[C@@H]5[C@@H](O)[C@@H]6O[C@H](CO)[C@H]5O[C@H]7O[C@H](CO)[C@@H](O[C@H]8O[C@H](CO)[C@@H](O[C@H]9O[C@H](CO)[C@@H](O[C@H]%10O[C@H](CO)[C@@H](O[C@H]%11O[C@H](CO)[C@@H](O[C@H]%12O[C@H](CO)[C@@H](O6)[C@H](O)[C@H]%12O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8OCCCO)[C@H](O)[C@H]7O

Description

  • General description: β-estradiol is a natural human estrogen. It is vital for the growth of breast and reproductive epithelia, maturation of long bones and development of secondary sexual characteristics.[1] Estradiol is produced by immature germ cells, spermatozoa, Leydig cells and Sertoli cells.[2] β-estradiol acts as a menopausal hormones. It is involved in replacement therapy for female hypogonadism or primary ovarian failure. Reduced levels of β-estradiol are linked to heart disease and osteoporosis.[1] Estradiol plays a critical role in proliferation, modulation of ion transport and control of apoptosis in Sertoli cells. It maintains sperm concentration, motility and morphology.[2]
  • Application: β-estradiol has been used:to culture differentiated adipocytes[3]for estradiol treatment in rats[4]for oocyte maturation in vitro[5]β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). This product is not recommended for use in binding assays.
  • Packaging: Package size based on estradiol
  • Other Notes: Contains 40-55 mg estradiol per gram of solid; balance 2-hydroxypropyl-β-cyclodextrin.

SAFETY INFORMATION

Pictograms

GHS08,GHS09

Signal Word

Danger

Hazard Statements

H351,H360FD,H362,H410

Precautionary Statements

P202 - P260 - P263 - P264 - P273 - P308 + P313

Hazard Classifications

Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A

WGK

WGK 3

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C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O.C[C@@H]5[C@@H](O)[C@@H]6O[C@H](CO)[C@H]5O[C@H]7O[C@H](CO)[C@@H](O[C@H]8O[C@H](CO)[C@@H](O[C@H]9O[C@H](CO)[C@@H](O[C@H]%10O[C@H](CO)[C@@H](O[C@H]%11O[C@H](CO)[C@@H](O[C@H]%12O[C@H](CO)[C@@H](O6)[C@H](O)[C@H]%12O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8OCCCO)[C@H](O)[C@H]7O

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