N8028

Nikkomycin Z from Streptomyces tendae

≥90% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 59456-70-1

Synonym(S): Neopolyoxin C, Nikkomycin Z

Select a Size

Pack Size SKU Availability Price
5 MG N8028-5-MG Out of stock ₹ 31,814.68

N8028 - 5 MG

₹ 31,814.68

Out of stock

Quantity

1

Base Price: ₹ 31,814.68

GST (18%): ₹ 5,726.642

Total Price: ₹ 37,541.322

Quality Level

200

Assay

≥90% (HPLC)

form

powder

solubility

H2O: soluble 5 mg/mL

antibiotic activity spectrum

fungi

Mode of action

cell wall synthesis | interferesenzyme | inhibits

storage temp.

2-8°C

SMILES string

C[C@@H]([C@H](N)C(=O)N[C@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O)C(O)=O)[C@H](O)c3ccc(O)cn3

InChI

1S/C20H25N5O10/c1-7(13(28)9-3-2-8(26)6-22-9)11(21)17(31)24-12(19(32)33)16-14(29)15(30)18(35-16)25-5-4-10(27)23-20(25)34/h2-7,11-16,18,26,28-30H,21H2,1H3,(H,24,31)(H,32,33)(H,23,27,34)/t7-,11-,12+,13-,14-,15+,16+,18+/m0/s1

InChI key

WWJFFVUVFNBJTN-JKEIIPFCSA-N

Other Options

Image Product Name Manufacturer Price Range
N8028
Nikkomycin Z from Streptomyces tendae
Sigma Aldrich ₹ 31,814.68
AG67868
59456-70-1 | Nikkomycin Z
A2B Chem ₹ 41,667.72 - ₹ 84,276.60

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Description

  • General description: Chemical structure: peptidyl nucleoside
  • Application: Nikkomycin Z is used as a selective competitive inhibitor of chitin synthetase 3 in studies on fungal cell wall development. It is a potential treatment for human Encephalitozoon hellem, a microsporidian species[1] and is used to study the changes of chitin and β--glucan under Nikkomycin Z exposure[2].
  • Biochem/physiol Actions: Nikkomycin Z inhibits chitin synthase from converting UDP-GlcNAc into cell wall chitin due to its structural resemblance to UDP-N-acetylglucosamine[3].
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

SAFETY INFORMATION

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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N8028

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Quality Level:
200

Assay:
≥90% (HPLC)

form:
powder

solubility:
H2O: soluble 5 mg/mL

antibiotic activity spectrum:
fungi

Mode of action:
cell wall synthesis | interferesenzyme | inhibits

storage temp.:
2-8°C

SMILES string:
C[C@@H]([C@H](N)C(=O)N[C@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O)C(O)=O)[C@H](O)c3ccc(O)cn3

InChI:
1S/C20H25N5O10/c1-7(13(28)9-3-2-8(26)6-22-9)11(21)17(31)24-12(19(32)33)16-14(29)15(30)18(35-16)25-5-4-10(27)23-20(25)34/h2-7,11-16,18,26,28-30H,21H2,1H3,(H,24,31)(H,32,33)(H,23,27,34)/t7-,11-,12+,13-,14-,15+,16+,18+/m0/s1

InChI key:
WWJFFVUVFNBJTN-JKEIIPFCSA-N

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