Penicillin-Streptomycin

Description

• General description: Penicillin, a β-lactam antibiotic is extremely active towards bacteria.[1] Penicillins are also termed as penams. It is naturally occurring and has a bicyclic skeleton.[2] Streptomycin is a pseudotrisaccharide. It comprises of a monosubstituted aminocyclitol.[3]
• Application: Penicillin-Streptomycin has been used: as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) to maintain the Huh7 liver hepatoma cell line[4]as a supplement in Roswell park memorial institute-1640 (RPMI) medium to maintain mouse lymphoma YAC-1 cells[5]as a component in minimum essential medium Eagle to treat individual mouse spleens for the preparation of splenocytes[6]as a supplement in FMX-8 complete medium to culture Chinese hamster ovary cells[7]
• Biochem/physiol Actions: Penicillins can prevent the synthesis of bacterial cell wall. This antibiotic can be used in the treatment of skin and urinary tract infections, upper and lower respiratory infections, and endocarditis.[8] Streptomycin can block Mycobacterium tuberculosis in vitro.[4] Streptomycin inhibits prokaryote protein synthesis[7] by preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding.
• Components: This product is formulated to contain 5,000 units penicillin and 5 mg streptomycin/mL solubilized in a proprietary citrate buffer.
• Other Notes: 20ml,100ml