P5333
Pleiotrophin human
≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): HARP, HB-GAM, Heparin affinity regulatory peptide, Heparin-binding growth factor, Heparin-binding growth-associated molecule, PTN
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 μG | P5333-50-μG | In Stock | ₹ 59,364.30 |
P5333 - 50 μG
In Stock
Quantity
1
Base Price: ₹ 59,364.30
GST (18%): ₹ 10,685.574
Total Price: ₹ 70,049.874
biological source
human
Quality Level
200
recombinant
expressed in baculovirus infected Sf21 cells
Assay
≥97% (SDS-PAGE)
form
lyophilized powder
mol wt
predicted mol wt 15.3 kDa
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
Related Products
Description
- General description: Pleiotrophin (PTN) is a multifunctional growth factor.[1] The protein coded by the PTN gene is a member of the heparin-binding cytokines family. This gene is located on human chromosome 7.[2] Pleiotrophin is also known as heparin-binding brain mitogen (HBBM), heparin-binding growth factor-8 (HBGF-8), heparin-binding growth-associated molecule (HB-GAM) and osteoblast-specific factor (OSF-1).[3] This gene is highly expressed in brain,[4] uterus, gut, muscle, lung and skin. Pleiotrophin mRNA is expressed in osteoblasts, chondrocytes, tumor cells,[5] fibroblasts, astrocytes and Schwann cells.
- Application: PTN is active in growth and development, and has mitogenic and neurite outgrowth activity. The gene for pleiotrophin is highly expressed in brain, uterus, gut, muscle, lung, and skin tissues
- Biochem/physiol Actions: Pleiotrophin participates in growth and development. Pleiotrophin is mitogenic and displays neurite outgrowth activity. It stimulates tumor angiogenesis.[6] There is extraordinary conservation between the amino acid sequences of bovine, human, and rat pleiotrophin.[3]
- Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
- Analysis Note: The activity is measured in culture by the ability to enhance neurite outgrowth of cerebral cortical neurons from rat embryos.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: human
Quality Level: 200
recombinant: expressed in baculovirus infected Sf21 cells
Assay: ≥97% (SDS-PAGE)
form: lyophilized powder
mol wt: predicted mol wt 15.3 kDa
packaging: pkg of 50 μg
storage condition: avoid repeated freeze/thaw cycles
technique(s): cell culture | mammalian: suitable
impurities: endotoxin, tested
biological source:
human
Quality Level:
200
recombinant:
expressed in baculovirus infected Sf21 cells
Assay:
≥97% (SDS-PAGE)
form:
lyophilized powder
mol wt:
predicted mol wt 15.3 kDa
packaging:
pkg of 50 μg
storage condition:
avoid repeated freeze/thaw cycles
technique(s):
cell culture | mammalian: suitable
impurities:
endotoxin, tested
biological source: __
Quality Level: 200
recombinant: __
Assay: ≥99%
form: solid
mol wt: __
packaging: __
storage condition: __
technique(s): __
impurities: __
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
≥99%
form:
solid
mol wt:
__
packaging:
__
storage condition:
__
technique(s):
__
impurities:
__
biological source: __
Quality Level: 200
recombinant: __
Assay: __
form: powder
mol wt: __
packaging: __
storage condition: __
technique(s): __
impurities: ≤0.0005% Phosphorus (P)≤0.1% Insoluble matter
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
__
form:
powder
mol wt:
__
packaging:
__
storage condition:
__
technique(s):
__
impurities:
≤0.0005% Phosphorus (P)≤0.1% Insoluble matter
biological source: __
Quality Level: 100
recombinant: __
Assay: 99%
form: powder
mol wt: __
packaging: __
storage condition: __
technique(s): __
impurities: __
biological source:
__
Quality Level:
100
recombinant:
__
Assay:
99%
form:
powder
mol wt:
__
packaging:
__
storage condition:
__
technique(s):
__
impurities:
__