Description

• General description: Chemical structure: peptidyl nucleoside
• Application: Recommended for use as a selection agent at a range of 1-10 μg/mL.
• Biochem/physiol Actions: Puromycin dihydrochloride is a part of the amino-nucleoside family of antibiotics and is derived from Streptomyces alboniger. It is a broad spectrum antibiotic with antitumor activity, as an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation. The recommended working concentration in eukaryotic cell culture is 1-10 μg/mL.
• Features and Benefits: This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
• Caution: As supplied, this product remains active for four years when stored at -20°C.
• Preparation Note: This product is soluble in water at 50 mg/mL. A stock solution should be prepared by filtration using a 0.22 μm filter and then stored in aliquots at -20°C. This product is also soluble in methanol at 10 mg/mL.
• Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place