SRP3129

NT-4 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): Neurotrophic 4/5 (NT-4/NT-5), Neurotrophin-4

Select a Size

Pack Size SKU Availability Price
10 μG SRP3129-10-μG In Stock ₹ 35,094.65

SRP3129 - 10 μG

₹ 35,094.65

In Stock

Quantity

1

Base Price: ₹ 35,094.65

GST (18%): ₹ 6,317.037

Total Price: ₹ 41,411.687

biological source

human

recombinant

expressed in E. coli

Assay

≥98% (HPLC)≥98% (SDS-PAGE)

form

lyophilized

potency

20-50 ng/mL ED50

mol wt

14.0 kDa

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

white to off-white

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Description

  • General description: NT-4 is a neurotrophic factor structurally related to b-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
  • Biochem/physiol Actions: NT-4 is a neurotrophic factor structurally related to b-NGF, BDNF, and NT-3. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
  • Sequence: GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
  • Physical form: Lyophilized with no additives.
  • Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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biological source:
human

recombinant:
expressed in E. coli

Assay:
≥98% (HPLC)≥98% (SDS-PAGE)

form:
lyophilized

potency:
20-50 ng/mL ED50

mol wt:
14.0 kDa

packaging:
pkg of 10 μg

technique(s):
cell culture | mammalian: suitable

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<0.1 EU/μg endotoxin, tested

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white to off-white

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