SRP3288

IL-36 BETA human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Manufacturer: Sigma Aldrich

Synonym(S): IL-1 eta, IL-1F8, IL-1H2

Select a Size

Pack Size SKU Availability Price
10 μG SRP3288-10-μG In Stock ₹ 34,720.80

SRP3288 - 10 μG

₹ 34,720.80

In Stock

Quantity

1

Base Price: ₹ 34,720.80

GST (18%): ₹ 6,249.744

Total Price: ₹ 40,970.544

biological source

human

recombinant

expressed in E. coli

Assay

≥98% (HPLC)≥98% (SDS-PAGE)

form

lyophilized

mol wt

17.3 kDa

packaging

pkg of 10 μg

impurities

<0.1 EU/μg endotoxin, tested

color

white to off-white

UniProt accession no.

Q9NZH8

shipped in

wet ice

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Description

  • General description: IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3.
  • Biochem/physiol Actions: The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.
  • Physical form: Lyophilized from 10 mM Sodium Phosphate, pH 7.0.
  • Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Sigma Aldrich

SRP3288

recombinant, expressed in E. coli, ...


biological source:
human

recombinant:
expressed in E. coli

Assay:
≥98% (HPLC)≥98% (SDS-PAGE)

form:
lyophilized

mol wt:
17.3 kDa

packaging:
pkg of 10 μg

impurities:
<0.1 EU/μg endotoxin, tested

color:
white to off-white

UniProt accession no.:
Q9NZH8

shipped in:
wet ice

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Assay:
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form:
lyophilized

mol wt:
17.0 kDa

packaging:
pkg of 10 μg

impurities:
<0.1 EU/μg endotoxin, tested

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white to off-white

UniProt accession no.:
Q9NZH7

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