SRP3288
IL-36 BETA human
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Manufacturer: Sigma Aldrich
Synonym(S): IL-1 eta, IL-1F8, IL-1H2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | SRP3288-10-μG | In Stock | ₹ 34,720.80 |
SRP3288 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 34,720.80
GST (18%): ₹ 6,249.744
Total Price: ₹ 40,970.544
biological source
human
recombinant
expressed in E. coli
Assay
≥98% (HPLC)≥98% (SDS-PAGE)
form
lyophilized
mol wt
17.3 kDa
packaging
pkg of 10 μg
impurities
<0.1 EU/μg endotoxin, tested
color
white to off-white
UniProt accession no.
Q9NZH8
shipped in
wet ice
Description
- General description: IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3.
- Biochem/physiol Actions: The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.
- Physical form: Lyophilized from 10 mM Sodium Phosphate, pH 7.0.
- Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
SAFETY INFORMATION
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
mol wt: 17.3 kDa
packaging: pkg of 10 μg
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
UniProt accession no.: Q9NZH8
shipped in: wet ice
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
mol wt:
17.3 kDa
packaging:
pkg of 10 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
UniProt accession no.:
Q9NZH8
shipped in:
wet ice
biological source: human
recombinant: expressed in E. coli
Assay: ≥95% (HPLC)≥95% (SDS-PAGE)
form: lyophilized
mol wt: 17.0 kDa
packaging: pkg of 10 μg
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
UniProt accession no.: Q9NZH7
shipped in: wet ice
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥95% (HPLC)≥95% (SDS-PAGE)
form:
lyophilized
mol wt:
17.0 kDa
packaging:
pkg of 10 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
UniProt accession no.:
Q9NZH7
shipped in:
wet ice
biological source: mouse
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
mol wt: 23.8 kDa
packaging: pkg of 10 μg
impurities: <0.1 EU/μg endotoxin, tested
color: __
UniProt accession no.: P21275
shipped in: wet ice
biological source:
mouse
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
mol wt:
23.8 kDa
packaging:
pkg of 10 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
__
UniProt accession no.:
P21275
shipped in:
wet ice
biological source: mouse
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
mol wt: 27.0 kDa
packaging: pkg of 50 μg
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
UniProt accession no.: P43027
shipped in: __
biological source:
mouse
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
mol wt:
27.0 kDa
packaging:
pkg of 50 μg
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
UniProt accession no.:
P43027
shipped in:
__