V5765

VEGF165

recombinant, expressed in HEK 293 cells, suitable for cell culture

Manufacturer: Sigma Aldrich

Select a Size

Pack Size SKU Availability Price
10 μG V5765-10-μG In Stock ₹ 26,954.25
50 μG V5765-50-μG In Stock ₹ 1,00,899.83

V5765 - 10 μG

₹ 26,954.25

In Stock

Quantity

1

Base Price: ₹ 26,954.25

GST (18%): ₹ 4,851.765

Total Price: ₹ 31,806.015

biological source

human

Quality Level

200

recombinant

expressed in HEK 293 cells

description

Vascular Endothelial Growth Factor 165 human

Assay

≥95% (SDS-PAGE)

form

lyophilized powder

potency

<10 ng/mL ED50

quality

endotoxin tested

mol wt

dimer 42 kDa (glycosylated)

packaging

pkg of 10 μgpkg of 50 μg

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Description

  • General description: VEGF165 is expressed in human HEK 293 cells as a glycosylated homodimer with an apparent molecular mass of 45 kDa. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
  • Biochem/physiol Actions: VEGF165 belongs to the PDGF/VEGF growth factor family characterized by the presence of eight conserved cysteine residues and a cystine knot structure.[1] VEGF is secreted by the majority of tumor cells and initiates angiogenesis by activating endothelial cells of existing blood vessels and promoting their migration.[2]VEGF has also been implicated in correlation with poor prognosis in breast cancer.[2]In addition, VEGF is released in rheumatoid arthritis in response to TNF-α, increasing endothelial permeability and stimulating angiogenesis (formation of capillaries).[3][4]
  • Analysis Note: The specific activity was determined by the dose-dependent stimulation of the proliferation of HUVEC cells (human umbilical vein endothelial cells).

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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recombinant, expressed in HEK 293 c...


biological source:
human

Quality Level:
200

recombinant:
expressed in HEK 293 cells

description:
Vascular Endothelial Growth Factor 165 human

Assay:
≥95% (SDS-PAGE)

form:
lyophilized powder

potency:
<10 ng/mL ED50

quality:
endotoxin tested

mol wt:
dimer 42 kDa (glycosylated)

packaging:
pkg of 10 μgpkg of 50 μg

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Assay:
≥95% (SDS-PAGE)

form:
lyophilized powder

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<10 ng/mL ED50

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endotoxin tested

mol wt:
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pkg of 10 μgpkg of 50 μg

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