Bovine Renal Artery Smooth Muscle Cells: BRASMC (Cryovial)

Description

• General description: Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.Bovine Renal Artery Smooth Muscle Cells (BRASMC) are derived from tunica intima and tunica media of normal bovine renal arteries. They are cryopreserved at second passage and can be cultured and propagated at least 12 population doublings. Studies show cyclosporine-induced renal artery smooth muscle contraction is associated with increases in the phosphorylation of specific contractile regulatory proteins1. The renal artery smooth muscle is uniquely refractory to angiotensin stimulation and may be protective in the role of the kidney in regulating blood pressure through the renin-angiotensin system2.Beall, A. et al, Biochem Biophys Acta., 1449(1):41-9 (1999)Whitney, E.G. et al, J. Surg. Res. 61(2):307-10 (1996)Products are for research use only. They are not intended for human, animal, or diagnostic application.Animal tissues were USDA inspected.
• Cell Line Origin: Artery
• Application: blood flow to kidneys
• Components: Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
• Preparation Note: 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSOCan be cultured at least 12 doublings
• Subculture Routine: Please refer to the BRASMC Culture Protocol.