UFH-001 Human Breast Cancer Cell Line

Description

• General description: The UFH-001 triple negative CAIX+ human breast cancer cell line constitutively expresses CAIX under both hypoxic and normoxic conditions, exhibits an aggressive TNBC phenotype in vivo, and supports tumor growth in a mouse xenograft model [1]. The constitutive expression of CAIX in UFH-001 cells facilitates its evaluation as a potential therapeutic target both in vitro and in vivo. Source:UFH-001 cells are derived from MCF-10A cells, a spontaneously immortalized breast cancer epithelial cell line originating from breast tissue of a healthy female patient [2]. UFH-001 cells were sorted for CAIX expression by flow cytometry [1].
• Cell Line Description: Cancer Cells
• Application: Research CategoryCancer
• Quality: • Each vial contains ≥ 1X10⁶ viable cells.• Cells are tested negative for HPV-16, HPV-18, Hepatitis A, B, C, and HIV-1 & 2 viruses by PCR.• Cells are verified to be of human origin and negative for inter-species contamination from rat, mouse, chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.• Cells are negative for mycoplasma contamination.• Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.
• Storage and Stability: Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
• Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.