Gibco™ CTS™ Essential 6 Medium

Description

• CTS Essential 6 Medium is a cGMP-manufactured, xeno-free, feeder-free medium that supports the reprogramming of somatic cells and the spontaneous or directed differentiation of human pluripotent stem cells (PSCs)
• The formulation is based on a medium originally developed by Guokai Chen, et al., in the laboratory of James Thomson (1)
• With only six essential components, CTS Essential 6 Medium helps minimize variability
• To complete your PSC workflow with a matching culture medium for the growth and expansion of PSCs, use CTS Essential 8 Medium
• CTS Essential 6 Medium: • Provides a flexible format to suit different applications • Facilitates regulatory filings through cGMP manufacturing and the availability of documentation • Simplifies the transition from bench to clinic through the direct replacement of RUO Essential 6 Medium Provides a flexible format CTS Essential 6 Medium does not contain bFGF or TGFβ and so can support the formation of embryoid bodies
• This medium can support the directed differentiation of various cell types and somatic cell reprogramming using a variety of methods
• Facilitates regulatory filings CTS Essential 6 Medium is manufactured at a site that uses methods and controls that conform with cGMP for medical devices, 21 CFR Part 820
• Our FDA-registered manufacturing site is ISO 13485-certified
• Full documentation traceability and convenient access to our Drug Master File (DMF) are available for CTS Essential 6 Medium
• Simplifies transition from bench to clinic CTS Essential 6 Medium contains the same six essential components as RUO Essential 6 Medium, and with its cGMP manufacturing process, this fully-defined formulation helps minimize variability
• Like RUO Essential 6 Medium, CTS Essential 6 Medium does not contain bFGF or TGF-beta, which inhibits differentiation and negatively affects reprogramming efficiency, respectively
• With its additional safety testing, including adventitious agents, CTS Essential 6 Medium enables a smooth transition from RUO Essential 6 Medium
• Commercialized in partnership with Cellular Dynamics International
• Reference 1
• Chen G, Gulbranson DR, Hou Z, Bolin JM, Ruotti V, Probasco MD, Smuga-Otto K, Howden SE, Diol NR, Propson NE, Wagner R, Lee GO, Antosiewicz-Bourget J, Teng JM, Thomson JA
• Chemically defined conditions for human iPSC derivation and culture
• Nat Methods
• 2011 8(5):424-9.