157260

1-Hydroxybenzotriazole hydrate

98% dry basis wetted with not less than 14 wt. % water, for peptide synthesis

Manufacturer: Sigma Aldrich

CAS Number: 123333-53-9

Synonym(S): HOBt Hydrate

Select a Size

Pack Size SKU Availability Price
25 G 157260-25-G In Stock ₹ 3,658.85

157260 - 25 G

₹ 3,658.85

In Stock

Quantity

1

Base Price: ₹ 3,658.85

GST (18%): ₹ 658.593

Total Price: ₹ 4,317.443

product name

1-Hydroxybenzotriazole hydrate, wetted with not less than 14 wt. % water, 98% dry basis

Quality Level

200

Assay

98% dry basis

form

solid

quality

synthesis grade

reaction suitability

reaction type: Addition Reactions

mp

155-158 °C (lit.)

application(s)

peptide synthesis

SMILES string

[H]O[H].On1nnc2ccccc12

InChI

1S/C6H5N3O.H2O/c10-9-6-4-2-1-3-5(6)7-8-9;/h1-4,10H;1H2

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Description

  • General description: 1-Hydroxybenzotriazole hydrate is a derivative of benzotriazole primarily used as a coupling reagent in peptide synthesis.[1][2][3]
  • Application: 1-Hydroxybenzotriazole hydrate can be used as a reagent:To synthesize β-peptides via microwave-assisted amino acid coupling.In the spot synthesis of glycopeptides.It can also be used as a deprotection agent for the removal of Fmoc (9-fluorenylmethoxycarbonyl) protecting group.

SAFETY INFORMATION

Pictograms

GHS02,GHS07

Signal Word

Danger

Hazard Statements

H207,H319,H412

Precautionary Statements

P210 - P212 - P230 - P233 - P280 - P370 + P380 + P375 - P501

Hazard Classifications

Aquatic Chronic 3 - Desen. Expl. 2 - Eye Irrit. 2

Supplementary Hazards

EUH044

WGK

WGK 1

Flash Point(F)

314.6 °F

Flash Point(C)

157 °C

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Sigma Aldrich

157260

98% dry basis wetted with not less ...


product name:
1-Hydroxybenzotriazole hydrate, wetted with not less than 14 wt. % water, 98% dry basis

Quality Level:
200

Assay:
98% dry basis

form:
solid

quality:
synthesis grade

reaction suitability:
reaction type: Addition Reactions

mp:
155-158 °C (lit.)

application(s):
peptide synthesis

SMILES string:
[H]O[H].On1nnc2ccccc12

InChI:
1S/C6H5N3O.H2O/c10-9-6-4-2-1-3-5(6)7-8-9;/h1-4,10H;1H2

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SMILES string:
CCOC(=O)[C@@H]1C[C@H]1C(=O)OCC

InChI:
1S/C9H14O4/c1-3-12-8(10)6-5-7(6)9(11)13-4-2/h6-7H,3-5H2,1-2H3/t6-,7-/m1/s1

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SMILES string:
[Br-].C1CC1[P+](c2ccccc2)(c3ccccc3)c4ccccc4

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1S/C21H20P.BrH/c1-4-10-18(11-5-1)22(21-16-17-21,19-12-6-2-7-13-19)20-14-8-3-9-15-20;/h1-15,21H,16-17H2;1H/q+1;/p-1

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SMILES string:
OCC([C@@H](O)[C@H](O)COP(O)(O)=O)=O

InChI:
1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h4-6,8-9H,1-2H2,(H2,10,11,12)/t4-,5-/m1/s1