54802
1-Hydroxybenzotriazole hydrate
≥97.0% dry basis (T), for peptide synthesis
Manufacturer: Sigma Aldrich
CAS Number: 123333-53-9
Synonym(S): HOBt Hydrate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 250 G | 54802-250-G | In Stock | ₹ 38,104.00 |
54802 - 250 G
In Stock
Quantity
1
Base Price: ₹ 38,104.00
GST (18%): ₹ 6,858.72
Total Price: ₹ 44,962.72
product name
1-Hydroxybenzotriazole hydrate, ≥97.0% dry basis (T)
Quality Level
200
Assay
≥97.0% dry basis (T)
form
solid
composition
water, ~12%
reaction suitability
reaction type: Addition Reactions
mp
155-158 °C (lit.)
solubility
DMF: 0.1 g/mL, clear
application(s)
peptide synthesis
SMILES string
[H]O[H].On1nnc2ccccc12
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 1-Hydroxybenzotriazole hydrate | Sigma Aldrich | ₹ 3,658.85 |
Related Products
Description
- General description: 1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids.[1] It is also used as a racemization suppressor during peptide synthesis.[2]
- Application: 1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare: Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.[2] Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.[3]
- Other Notes: Widely used additive to decrease racemization in the carbodiimide peptide coupling;[4] Racemization-free condensation of peptide fragments[5][6]
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P210 - P212 - P230 - P233 - P280 - P370 + P380 + P375 - P501
Hazard Classifications
Aquatic Chronic 3 - Desen. Expl. 2 - Eye Irrit. 2
WGK
WGK 1
Flash Point(F)
314.6 °F
Flash Point(C)
157 °C
Compare Similar Items
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product name: 1-Hydroxybenzotriazole hydrate, ≥97.0% dry basis (T)
Quality Level: 200
Assay: ≥97.0% dry basis (T)
form: solid
composition: water, ~12%
reaction suitability: reaction type: Addition Reactions
mp: 155-158 °C (lit.)
solubility: DMF: 0.1 g/mL, clear
application(s): peptide synthesis
SMILES string: [H]O[H].On1nnc2ccccc12
product name:
1-Hydroxybenzotriazole hydrate, ≥97.0% dry basis (T)
Quality Level:
200
Assay:
≥97.0% dry basis (T)
form:
solid
composition:
water, ~12%
reaction suitability:
reaction type: Addition Reactions
mp:
155-158 °C (lit.)
solubility:
DMF: 0.1 g/mL, clear
application(s):
peptide synthesis
SMILES string:
[H]O[H].On1nnc2ccccc12
product name: __
Quality Level: 100
Assay: __
form: __
composition: bed wt., 400 mg
reaction suitability: __
mp: __
solubility: __
application(s): __
SMILES string: __
product name:
__
Quality Level:
100
Assay:
__
form:
__
composition:
bed wt., 400 mg
reaction suitability:
__
mp:
__
solubility:
__
application(s):
__
SMILES string:
__
product name: __
Quality Level: 100
Assay: 97%
form: __
composition: __
reaction suitability: __
mp: 69-73 °C (lit.)
solubility: __
application(s): __
SMILES string: Clc1cc(ccn1)C#N
product name:
__
Quality Level:
100
Assay:
97%
form:
__
composition:
__
reaction suitability:
__
mp:
69-73 °C (lit.)
solubility:
__
application(s):
__
SMILES string:
Clc1cc(ccn1)C#N
product name: __
Quality Level: 100
Assay: ≥98.0% (HPLC)
form: __
composition: __
reaction suitability: __
mp: 230 °C (dec.) (lit.)
solubility: __
application(s): food and beverages
SMILES string: Oc1ccc2C=CC(=O)Oc2c1
product name:
__
Quality Level:
100
Assay:
≥98.0% (HPLC)
form:
__
composition:
__
reaction suitability:
__
mp:
230 °C (dec.) (lit.)
solubility:
__
application(s):
food and beverages
SMILES string:
Oc1ccc2C=CC(=O)Oc2c1