41996

1-Hydroxy-7-azabenzotriazole solution

~0.6 M in DMF, for peptide synthesis

Manufacturer: Sigma Aldrich

CAS Number: 39968-33-7

Synonym(S): 3H-[1,2,3]-Triazolo[4,5-b]pyridin-3-ol, HOAt

Select a Size

Pack Size SKU Availability Price
100 ML 41996-100-ML In Stock ₹ 51,819.28

41996 - 100 ML

₹ 51,819.28

In Stock

Quantity

1

Base Price: ₹ 51,819.28

GST (18%): ₹ 9,327.47

Total Price: ₹ 61,146.75

product name

1-Hydroxy-7-azabenzotriazole solution, ~0.6 M in DMF

form

liquid

Quality Level

100

reaction suitability

reaction type: Addition Reactions

concentration

~0.6 M in DMF

impurities

<1.0% water

refractive index

n20/D 1.441

density

0.978 g/mL at 20 °C

application(s)

peptide synthesis

SMILES string

On1nnc2cccnc12

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Description

  • General description: 1-Hydroxy-7-azabenzotriazole solution, also known as 3H-[1,2,3]-triazolo[4,5-b]pyridin-3-ol, is a benzotriazolic additive that is commonly used as a coupling reagent for amino acids and peptides. It is also used to minimize epimerization. [1] [2]
  • Application: 1-Hydroxy-7-azabenzotriazole solution is used as a reagent in the solid-phase synthesis of chiral peptide nucleic acids. [3]
  • Other Notes: Coupling additive for efficient racemization-free coupling in peptide synthesis;[4][5][6] segment coupling.[7]

SAFETY INFORMATION

Pictograms

GHS02,GHS08,GHS07

Signal Word

Danger

Hazard Statements

H226,H312 + H332,H319,H360D

Precautionary Statements

P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

WGK

WGK 3

Flash Point(F)

136.4 °F

Flash Point(C)

58 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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41996

~0.6 M in DMF, for peptide synthesi...


product name:
1-Hydroxy-7-azabenzotriazole solution, ~0.6 M in DMF

form:
liquid

Quality Level:
100

reaction suitability:
reaction type: Addition Reactions

concentration:
~0.6 M in DMF

impurities:
<1.0% water

refractive index:
n20/D 1.441

density:
0.978 g/mL at 20 °C

application(s):
peptide synthesis

SMILES string:
On1nnc2cccnc12

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