251569

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

98%, for peptide synthesis

Manufacturer: Sigma Aldrich

CAS Number: 7226-23-5

Synonym(S): 1,3-Dimethyl-2-oxohexahydropyrimidine, N,N′-Dimethylpropylene urea, DMPU

Select a Size

Pack Size SKU Availability Price
25 G 251569-25-G In Stock ₹ 2,186.70
100 G 251569-100-G In Stock ₹ 4,784.10
500 G 251569-500-G In Stock ₹ 16,827.60

251569 - 25 G

₹ 2,186.70

In Stock

Quantity

1

Base Price: ₹ 2,186.70

GST (18%): ₹ 393.606

Total Price: ₹ 2,580.306

product name

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 98%

Quality Level

200

Assay

98%

form

liquid

refractive index

n20/D 1.488 (lit.)

bp

146 °C/44 mmHg (lit.)

density

1.06 g/mL at 25 °C (lit.)

application(s)

peptide synthesis

SMILES string

CN1CCCN(C)C1=O

InChI

1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3

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Description

  • Application: 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) can be used:As a versatile solvent in N-alkylation of amines [1]O-alkylation of aldoses [2], and in the synthesis of poly(aryl ethers).[3]As urea solvent in the synthesis of 1-aryl-3,4,5-substituted pyrazoles by cyclocondensation of arylhydrazine hydrochlorides with 1,3-diketones.[4]As an additive in asymmetric cyanoamidation.[5]DMPU/HF can be used as a nucleophilic fluorinating agent in fluoro-Prins reaction for the synthesis of substituted 4-fluorotetrahydropyrans and 4-fluoropiperidines.[6]

SAFETY INFORMATION

Pictograms

GHS08,GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H318,H361f

Precautionary Statements

P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

WGK

WGK 1

Flash Point(F)

249.8 °F

Flash Point(C)

121 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sigma Aldrich

251569

98%, for peptide synthesis...


product name:
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 98%

Quality Level:
200

Assay:
98%

form:
liquid

refractive index:
n20/D 1.488 (lit.)

bp:
146 °C/44 mmHg (lit.)

density:
1.06 g/mL at 25 °C (lit.)

application(s):
peptide synthesis

SMILES string:
CN1CCCN(C)C1=O

InChI:
1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3

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Sigma Aldrich

251631

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form:
powder

refractive index:
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density:
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SMILES string:
[K+].[O-]S(=O)(=O)CCCOC(=O)C=C

InChI:
1S/C6H10O5S.K/c1-2-6(7)11-4-3-5-12(8,9)10;/h2H,1,3-5H2,(H,8,9,10);/q;+1/p-1

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SMILES string:
[K+].CC(=C)C(=O)OCCCS([O-])(=O)=O

InChI:
1S/C7H12O5S.K/c1-6(2)7(8)12-4-3-5-13(9,10)11;/h1,3-5H2,2H3,(H,9,10,11);/q;+1/p-1

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SMILES string:
[Na+].[O-]S(=O)(=O)CCCS

InChI:
1S/C3H8O3S2.Na/c4-8(5,6)3-1-2-7;/h7H,1-3H2,(H,4,5,6);/q;+1/p-1