8.52031
Fmoc-Cys(Mmt)-OH
≥99% (TLC), for peptide synthesis, Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 177582-21-7
Synonym(S): Fmoc-Cys(Mmt)-OH, N-α-Fmoc-S-p-methoxytrityl-L-cysteine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 8.52031-1-G | In Stock | ₹ 5,800.01 |
| 5 G | 8.52031-5-G | In Stock | ₹ 22,899.99 |
| 25 G | 8.52031-25-G | In Stock | ₹ 85,589.99 |
| 8520310100 | 8.52031-8520310100 | In Stock | ₹ 3,13,120.00 |
8.52031 - 1 G
In Stock
Quantity
1
Base Price: ₹ 5,800.01
GST (18%): ₹ 1,044.002
Total Price: ₹ 6,844.012
product name
Fmoc-Cys(Mmt)-OH, Novabiochem®
Quality Level
200
product line
Novabiochem®
Assay
≥85.0% (acidimetric)≥98.0% (HPLC)≥99% (TLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
thiol
storage temp.
15-25°C
Other Options
Related Products
Description
- General description: Building block for Fmoc SPPS which enables selective deprotection of cysteinyl thiol group on the solid phase. The Mmt group can be removed on the solid phase with 1% TFA in DCM containing 5% TIS [1,2,3,4]. Reference 4 describes a novel method for on-resin disulfide bond formation which uses Cys(Mmt) in combination with Cys(tBuS).Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPS Fmoc SPPS of Cysteine-Containing PeptidesLiterature references [1] K. Barlos, et al. in ′Peptides 1992, Proc. 22nd European Peptide Symposium′, C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283. [2] C. Kellenberger, et al. (1995) Pept. Res., 8, 321. [3] K. Barlos, et al. (1996) Int. J. Peptide Protein Res., 47, 148. [4] A. K. Galande, et al. (2005) J. Comb. Chem., 7, 174.
- Application: An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide: Details the use of Fmoc-Cys(Mmt)-OH in the synthesis of Eptifibatide, highlighting its role in a cGMP-ready process (Sabatino et al., 2020).
- Linkage: Replaces: 04-12-1061
- Analysis Note: Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testEnantiomeric purity: ≥ 99.0 % (a/a)Purity (TLC(011A)): ≥ 99 %Purity (TLC(0811)): ≥ 99 %Assay (HPLC, area%): ≥ 98.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly solubleAssay (acidimetric): ≥ 85.0 %Water (K. F.): ≤ 1.0 %To see the solvent systems used for TLC of Novabiochem® products please click here.
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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product name: Fmoc-Cys(Mmt)-OH, Novabiochem®
Quality Level: 200
product line: Novabiochem®
Assay: ≥85.0% (acidimetric)≥98.0% (HPLC)≥99% (TLC)
form: powder
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename: Novabiochem®
application(s): peptide synthesis
functional group: thiol
storage temp.: 15-25°C
product name:
Fmoc-Cys(Mmt)-OH, Novabiochem®
Quality Level:
200
product line:
Novabiochem®
Assay:
≥85.0% (acidimetric)≥98.0% (HPLC)≥99% (TLC)
form:
powder
reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename:
Novabiochem®
application(s):
peptide synthesis
functional group:
thiol
storage temp.:
15-25°C
product name: __
Quality Level: 400
product line: Novabiochem®
Assay: ≥97.0% (acidimetric)≥98% (TLC)≥99.0% (HPLC)
form: powder
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename: Novabiochem®
application(s): peptide synthesis
functional group: Fmoc
storage temp.: −20°C (−15°C to −25°C)
product name:
__
Quality Level:
400
product line:
Novabiochem®
Assay:
≥97.0% (acidimetric)≥98% (TLC)≥99.0% (HPLC)
form:
powder
reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename:
Novabiochem®
application(s):
peptide synthesis
functional group:
Fmoc
storage temp.:
−20°C (−15°C to −25°C)
product name: __
Quality Level: 200
product line: Novabiochem®
Assay: ≥95.0% (acidimetric)≥98% (TLC)≥98.0% (HPLC)
form: powder
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename: Novabiochem®
application(s): peptide synthesis
functional group: hydroxyl
storage temp.: 2-30°C
product name:
__
Quality Level:
200
product line:
Novabiochem®
Assay:
≥95.0% (acidimetric)≥98% (TLC)≥98.0% (HPLC)
form:
powder
reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename:
Novabiochem®
application(s):
peptide synthesis
functional group:
hydroxyl
storage temp.:
2-30°C
product name: __
Quality Level: 200
product line: Novabiochem®
Assay: ≥85.0% (acidimetric)≥98% (TLC)≥98.0% (HPLC)
form: powder
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename: Novabiochem®
application(s): peptide synthesis
functional group: amine
storage temp.: 15-25°C
product name:
__
Quality Level:
200
product line:
Novabiochem®
Assay:
≥85.0% (acidimetric)≥98% (TLC)≥98.0% (HPLC)
form:
powder
reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename:
Novabiochem®
application(s):
peptide synthesis
functional group:
amine
storage temp.:
15-25°C