Fmoc-Glu-ODmab
Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 172611-75-5
Synonym(S): Fmoc-Glu-ODmab, N-α-Fmoc-L-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 8.52077-1-G | In Stock | ₹ 22,149.99 |
| 5 G | 8.52077-5-G | In Stock | ₹ 88,700.00 |
8.52077 - 1 G
In Stock
Quantity
1
Base Price: ₹ 22,149.99
GST (18%): ₹ 3,986.998
Total Price: ₹ 26,136.988
Quality Level
200
product line
Novabiochem®
Assay
≥90% (TLC)≥96.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
carboxylic acid
storage temp.
15-25°C
InChI
1S/C40H44N2O8/c1-24(2)19-33(37-34(43)20-40(3,4)21-35(37)44)41-26-15-13-25(14-16-26)22-49-36(45)18-17-32(38(46)47)42-39(48)50-23-31-29-11-7-5-9-27(29)28-10-6-8-12-30(28)31/h5-16,24,31-32,41H,17-23H2,1-4H3,(H,42,48)(H,46,47)
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Description
- General description: Quasi-orthogonally-protected Glu derivative. The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Glu(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSLiterature references[1] W. C. Chan, et al. (1995) J. Chem. Soc., Chem. Commun., 2209.
- Linkage: Replaces: 04-12-1174
- Analysis Note: Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testEnantiomeric purity: ≥ 99.5 % (a/a)Purity (TLC(011A)): ≥ 90 %Purity (TLC(0811)): ≥ 90 %Assay (HPLC, area%): ≥ 96.0 % (a/a)To see the solvent systems used for TLC of Novabiochem® products please click here.
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Quality Level: 200
product line: Novabiochem®
Assay: ≥90% (TLC)≥96.0% (HPLC)
form: powder
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename: Novabiochem®
application(s): peptide synthesis
functional group: carboxylic acid
storage temp.: 15-25°C
InChI: 1S/C40H44N2O8/c1-24(2)19-33(37-34(43)20-40(3,4)21-35(37)44)41-26-15-13-25(14-16-26)22-49-36(45)18-17-32(38(46)47)42-39(48)50-23-31-29-11-7-5-9-27(29)28-10-6-8-12-30(28)31/h5-16,24,31-32,41H,17-23H2,1-4H3,(H,42,48)(H,46,47)
Quality Level: 200
product line: Novabiochem®
Assay: ≥95.0% (HPLC)≥97% (TLC)
form: powder
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename: Novabiochem®
application(s): peptide synthesis
functional group: carboxylic acid
storage temp.: 15-25°C
InChI: __
Quality Level: 200
product line: Novabiochem®
Assay: ≥98% (TLC)≥99.0% (HPLC)
form: powder
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename: Novabiochem®
application(s): peptide synthesis
functional group: hydroxyl
storage temp.: 2-8°C
InChI: __