8.52090

Fmoc-Tyr(PO(NMe₂)₂)-OH

Novabiochem®

Manufacturer: Sigma Aldrich

CAS Number: 172611-23-3

Synonym(S): Fmoc-Tyr(PO(NMe₂)₂)-OH, N-α-Fmoc-O-(bis-dimethylamino-phosphono)-L-tyrosine

Select a Size

Pack Size SKU Availability Price
1 G 8.52090-1-G In Stock ₹ 20,270.00
5 G 8.52090-5-G In Stock ₹ 81,390.00
8520900025 8.52090-8520900025 In Stock ₹ 3,00,220.00
8520900100 8.52090-8520900100 In Stock ₹ 8,96,460.00
8520900500 8.52090-8520900500 In Stock ₹ 37,57,790.01

8.52090 - 1 G

₹ 20,270.00

In Stock

Quantity

1

Base Price: ₹ 20,270.00

GST (18%): ₹ 3,648.60

Total Price: ₹ 23,918.60

Quality Level

200

product line

Novabiochem®

Assay

≥93.0% (acidimetric)≥96% (TLC)≥96.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

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Description

  • General description: Fmoc-Tyr(PO(NMe2)2)-OH is a useful derivative for the synthesis of phosphotyrosine-containing peptides by Fmoc SPPS [1]. As the side-chain phosphate group is fully protected, this derivative is compatible with all coupling methods.Regeneration of phosphotyrosine from the phosphodiamidate is effected by acid catalyzed hydrolysis using 90% aq. TFA. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSLiterature references[1] H. G. Chao, et al. (1995) J. Org. Chem., 60, 7710.
  • Linkage: Replaces: 04-12-1205
  • Analysis Note: Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testEnantiomeric purity: ≥ 99.5 % (a/a)Purity (TLC(0811)): ≥ 98 %Assay (HPLC, area%): ≥ 96.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly solubleAssay (acidimetric): ≥ 93.0 %Water (K. F.): ≤ 4.5 %Ethyl acetate (HS-GC): ≤ 0.5 %Acetate (IC): ≤ 0.1 %To see the solvent systems used for TLC of Novabiochem® products please click here.
  • Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Quality Level:
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Assay:
≥93.0% (acidimetric)≥96% (TLC)≥96.0% (HPLC)

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reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis

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peptide synthesis

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reaction suitability:
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peptide synthesis

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