8.52182

Fmoc-Tyr(tBu)-Thr(psiMe,Mepro)-OH

Novabiochem®

Manufacturer: Sigma Aldrich

CAS Number: 920519-31-9

Synonym(S): Fmoc-Tyr(tBu)-Thr(psiMe,Mepro)-OH

Select a Size

Pack Size SKU Availability Price
1 G 8.52182-1-G In Stock ₹ 7,138.78
5 G 8.52182-5-G In Stock ₹ 28,520.00
8521820025 8.52182-8521820025 In Stock ₹ 1,31,720.00
8521820100 8.52182-8521820100 In Stock ₹ 3,52,750.00

8.52182 - 1 G

₹ 7,138.78

In Stock

Quantity

1

Base Price: ₹ 7,138.78

GST (18%): ₹ 1,284.98

Total Price: ₹ 8,423.76

Quality Level

200

product line

Novabiochem®

Assay

≥97% (TLC)≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-8°C

InChI

1S/C35H40N2O7/c1-21-30(32(39)40)37(35(5,6)43-21)31(38)29(19-22-15-17-23(18-16-22)44-34(2,3)4)36-33(41)42-20-28-26-13-9-7-11-24(26)25-12-8-10-14-27(25)28/h7-18,21,28-30H,19-20H2,1-6H3,(H,36,41)(H,39,40)/t21-,29+,30+/m1/s1

Other Options

Image Product Name Manufacturer Price Range
AH84703
920519-31-9 | Fmoc-tyr(tbu)-thr(psime,mepro)-oh
A2B Chem ₹ 2,566.80 - ₹ 23,357.88

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Description

  • General description: This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Tyr-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSOvercoming Aggregation in Fmoc SPPS
  • Linkage: Replaces: 05-20-1007
  • Analysis Note: Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testOptical rotation α 25/D (c=1 in methanol): -32.0 - -26.0 °Purity (TLC(157A)): ≥ 97 %Purity (TLC(CMA2)): ≥ 97 %Assay (HPLC, area%): ≥ 97.0 % (a/a)Single impurities (HPLC, area%): ≤ 1.00 % (a/a)Ethyl acetate (HS-GC): ≤ 2.0 %Acetate (IC): ≤ 0.1 %To see the solvent systems used for TLC of Novabiochem® products please click here.
  • Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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8.52182

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Quality Level:
200

product line:
Novabiochem®

Assay:
≥97% (TLC)≥97.0% (HPLC)

form:
powder

reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
hydroxyl

storage temp.:
2-8°C

InChI:
1S/C35H40N2O7/c1-21-30(32(39)40)37(35(5,6)43-21)31(38)29(19-22-15-17-23(18-16-22)44-34(2,3)4)36-33(41)42-20-28-26-13-9-7-11-24(26)25-12-8-10-14-27(25)28/h7-18,21,28-30H,19-20H2,1-6H3,(H,36,41)(H,39,40)/t21-,29+,30+/m1/s1

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8.52183

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Quality Level:
200

product line:
Novabiochem®

Assay:
≥97% (TLC)≥97.0% (HPLC)

form:
powder

reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
hydroxyl

storage temp.:
2-8°C

InChI:
__

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Sigma Aldrich

8.52184

≥97.0% (HPLC), for peptide synthesi...


Quality Level:
200

product line:
Novabiochem®

Assay:
≥97% (TLC)≥97.0% (HPLC)

form:
powder

reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
hydroxyl

storage temp.:
2-8°C

InChI:
__

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Sigma Aldrich

8.52186

≥97.0% (HPLC), for peptide synthesi...


Quality Level:
200

product line:
Novabiochem®

Assay:
≥97% (TLC)≥97.0% (HPLC)

form:
powder

reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
hydroxyl

storage temp.:
2-8°C

InChI:
__