8.52418

Fmoc-Asp(OBno)-OH

for peptide synthesis, Novabiochem®

Manufacturer: Sigma Aldrich

Synonym(S): Fmoc-Asp(OBno)-OH

Select a Size

Pack Size SKU Availability Price
1 G 8.52418-1-G In Stock ₹ 23,849.99
5 G 8.52418-5-G In Stock ₹ 94,280.00

8.52418 - 1 G

₹ 23,849.99

In Stock

Quantity

1

Base Price: ₹ 23,849.99

GST (18%): ₹ 4,292.998

Total Price: ₹ 28,142.988

product name

Fmoc-Asp(OBno)-OH, Novabiochem®

Quality Level

200

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

carboxylic acid

storage temp.

−20°C (−15°C to −25°C)

Related Products

Img

Sigma Aldrich

8.52413

for peptide synthesis, Novabiochem®...

Img

Sigma Aldrich

8.52401

Novabiochem®...

Img

Sigma Aldrich

8.52154

≥99.0% (HPLC), for peptide synthesi...

Img

Sigma Aldrich

8.52069

≥97% (TLC), for peptide synthesis, ...

Img

Sigma Aldrich

8.52347

≥95.0% (HPLC), for peptide synthesi...

Img

Sigma Aldrich

8.52351

≥98.0% (HPLC), for peptide synthesi...

Img

Sigma Aldrich

8.52076

≥98% (TLC), for peptide synthesis, ...

Img

Sigma Aldrich

8.52122

≥98.0% (acidimetric), for peptide s...

Description

  • General description: An excellent derivative for minimizing aspartimide formation during Fmoc SPPS, including those containing the Asp-Gly sequence. The bulky OBno protecting group offers considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu and OMpe group.[1],[2] Associated Protocols and Technical Articles Cleavage and Deprotection Protocols for Fmoc SPPS Overcoming Aspartimide Formation in Fmoc SPPSLiterature references:[1] R. Behrendt, et al. (2015) J. Pept. Sci., 21, 680.[2] R. Behrendt, et al. (2016) J. Pept. Sci., 22, 92.
  • Application: Recently, Fmoc-Asp(OBno)-OH has been used in the synthesis of the mini-protein Omomyc, which has been shown to repress MYC-dependent gene transcription.[3],[4]
  • Analysis Note: Color (visual): white to beigeAppearance of substance (visual): powder, chunks or crystalsIdentity (IR): passes testPurity (TLC (018A)): ≥ 95 %Enantiomeric purity: ≥ 99.5 % (a/a)Assay (HPLC, area%): ≥ 97.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly solubleTo see the solvent systems used for TLC of Novabiochem® products please click here.
  • Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

8.52418

for peptide synthesis, Novabiochem®...


product name:
Fmoc-Asp(OBno)-OH, Novabiochem®

Quality Level:
200

product line:
Novabiochem®

form:
powder

reaction suitability:
reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
carboxylic acid

storage temp.:
−20°C (−15°C to −25°C)

Img

Sigma Aldrich

8.53000

Novabiochem®...


product name:
__

Quality Level:
200

product line:
Novabiochem®

form:
powder

reaction suitability:
reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
__

storage temp.:
2-30°C

Img

Sigma Aldrich

8.53001

Novabiochem®...


product name:
__

Quality Level:
200

product line:
Novabiochem®

form:
powder

reaction suitability:
reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
__

storage temp.:
2-30°C

Img

Sigma Aldrich

8.53002

Novabiochem®...


product name:
__

Quality Level:
200

product line:
Novabiochem®

form:
powder

reaction suitability:
reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename:
Novabiochem®

application(s):
peptide synthesis

functional group:
__

storage temp.:
2-30°C