H-Cys(Trt)-2-ClTrt resin

Description

• General description: Pre-loaded resin for synthesis of protected peptide acids containing a C-terminal cysteine amino-acid residue by Fmoc SPPS. Cleavage of the protected peptide is effected by treatment with 1% TFA in DCM or 20% TFE in C649 DCM. The use of this resin enables the synthesis of peptides containing C-terminal cysteine without risk of racemization or β-piperidinylalanine formation. Associated Protocols and Technical Articles Cleavage and Deprotection Protocols for Fmoc SPPS
• Linkage: Replaces: 04-12-2811
• Analysis Note: Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.90 mmol/gSwelling Volume (in DMF): lot specific resultIdentity (of the substitution): passes testThe polymer matrix is copoly (styrene-1 % DVB), 200 - 400 mesh.
• Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany