699500P
Kdo2-Lipid A (KLA)
Manufacturer: Sigma Aldrich
CAS Number: 1246298-62-3
Synonym(S): KLA
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 699500P-1-MG | In Stock | ₹ 30,461.55 |
699500P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 30,461.55
GST (18%): ₹ 5,483.079
Total Price: ₹ 35,944.629
description
Di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt)
Assay
>99% (HPLC)
form
powder
packaging
pkg of 1 × 1 mg (699500P-1mg)
manufacturer/tradename
Avanti Polar Lipids
application(s)
lipidomics
lipid type
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO[C@]2(C([O-])=O)C[C@@H](O[C@@]3(C([O-])=O)O[C@H]([C@H](O)CO)[C@H](O)[C@H](O)C3)[C@@H](O)[C@@H]([C@H](O)CO)O2)[C@@H](OP([O-])(O)=O)[C@@H]1OC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCC
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 1246298-62-3 | Di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt) | A2B Chem | ₹ 79,143.00 |
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Description
- General description: A new preparation of the saccharolipid glycan, Kdo2-Lipid A (KLA), is a nearly homogeneous Re lipopolysaccharide (LPS) substructure with endotoxin activity equal to that of native LPS. KLA is comparable to LPS and its activity is reduced by >103 in cells from TLR-4 deficient mice. The advantage of KLA over LPS is that it is a reproducible, defined natural product, and it can be detected by ESI/MS at the low concentrations used to stimulate animal cells. The purity of KLA should also facilitate the structural analysis of its complexes with signaling receptors, such as TLR-4/MD2. New research* shows 1μg KLA induces the same response as 10μg LPS.Perform experiments at half the cost of using LPS!
- Application: Kdo2-Lipid A (KLA) has been used to study its role in lipopolysaccharide induced prion protein conversion.[1]
- Biochem/physiol Actions: Kdo2-Lipid A might be useful to stimulate inflammatory response.[4]
- Packaging: 2 mL Amber Glass Crimp Cap Vial (699500P-1mg)
- Other Notes: For R&D use only. Not for drug, household, or other uses.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
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description: Di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt)
Assay: >99% (HPLC)
form: powder
packaging: pkg of 1 × 1 mg (699500P-1mg)
manufacturer/tradename: Avanti Polar Lipids
application(s): lipidomics
lipid type: bioactive lipids
shipped in: dry ice
storage temp.: −20°C
SMILES string: O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO[C@]2(C([O-])=O)C[C@@H](O[C@@]3(C([O-])=O)O[C@H]([C@H](O)CO)[C@H](O)[C@H](O)C3)[C@@H](O)[C@@H]([C@H](O)CO)O2)[C@@H](OP([O-])(O)=O)[C@@H]1OC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCC
description:
Di[3-deoxy-D-manno-octulosonyl]-lipid A (ammonium salt)
Assay:
>99% (HPLC)
form:
powder
packaging:
pkg of 1 × 1 mg (699500P-1mg)
manufacturer/tradename:
Avanti Polar Lipids
application(s):
lipidomics
lipid type:
bioactive lipids
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO[C@]2(C([O-])=O)C[C@@H](O[C@@]3(C([O-])=O)O[C@H]([C@H](O)CO)[C@H](O)[C@H](O)C3)[C@@H](O)[C@@H]([C@H](O)CO)O2)[C@@H](OP([O-])(O)=O)[C@@H]1OC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCC
description: __
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description: __
Assay: 97%
form: powder
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storage temp.: −20°C
SMILES string: COc1cc(c(OP2Oc3ccccc3-c4ccccc4O2)c(c1)C(C)(C)C)-c5cc(OC)cc(c5OP6Oc7ccccc7-c8ccccc8O6)C(C)(C)C
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Assay:
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form:
powder
packaging:
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manufacturer/tradename:
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application(s):
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lipid type:
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shipped in:
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storage temp.:
−20°C
SMILES string:
COc1cc(c(OP2Oc3ccccc3-c4ccccc4O2)c(c1)C(C)(C)C)-c5cc(OC)cc(c5OP6Oc7ccccc7-c8ccccc8O6)C(C)(C)C
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manufacturer/tradename: Novagen®
application(s): __
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shipped in: dry ice
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description:
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form:
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manufacturer/tradename:
Novagen®
application(s):
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shipped in:
dry ice
storage temp.:
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SMILES string:
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