700059P
27-hydroxycholesterol-d6
Manufacturer: Sigma Aldrich
CAS Number: 1246302-95-3
Synonym(S): 25,26,26,26,27,27-hexadeuterocholest-5-ene-3β,27-diol; 27-hydroxycholest-5-en-3-ol(d6); 111011
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 700059P-1-MG | In Stock | ₹ 51,278.03 |
700059P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 51,278.03
GST (18%): ₹ 9,230.045
Total Price: ₹ 60,508.075
description
25,26,26,26,27,27-hexadeuterocholest-5-ene-3β,27-diol
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700059P-1mg)
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC[C@@]([2H])(C([2H])([2H])[2H])C(O)([2H])[2H]
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 27-hydroxycholesterol (D6) | Sigma Aldrich | ₹ 19,333.45 |
Related Products
Description
- General description: 27-hydroxycholesterol (27-HC) is synthesized from cholesterol by the action of sterol 27-hydroxylase in the liver. It is an abundant oxysterol in the circulation ranging from 0.15 to 0.73 μM. 27-HC serves as a substrate for bile synthesis.[1] 27-hydroxycholesterol-d6 is a deuterated form of 27-hydroxycholesterol.
- Application: 27-hydroxycholesterol-d6 has been used: as an internal standard in isotope dilution-mass spectrometry analysis of heart mitochondria samples[2] as an internal standard in gas chromatography-mass spectrometry (GC–MS) for plasma sterol quantification[3]as a deuterated internal standard for spiking plasma samples for liquid chromatography with tandem mass spectrometry (LC-MS-MS) analysis[4]
- Biochem/physiol Actions: 27-hydroxycholesterol (27-HC) is a weak liver X receptor (LXR) agonist[5] and a selective estrogen receptor modulator (SERM).[6] Elevated levels of 27-HC is observed in hypercholesterolemia.[7] 27-HC is implicated in breast cancer tumor[8] and glioblastoma progression.[9] 27-HC may help in treating non-alcoholic steatohepatitis. Elevated levels of 27-HC is associated with atherosclerotic lesions.[1]
- Packaging: 5 mL Amber Glass Screw Cap Vial (700059P-1mg)
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
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Show Difference
description: 25,26,26,26,27,27-hexadeuterocholest-5-ene-3β,27-diol
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 1 mg (700059P-1mg)
manufacturer/tradename: Avanti Polar Lipids
shipped in: dry ice
storage temp.: −20°C
SMILES string: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC[C@@]([2H])(C([2H])([2H])[2H])C(O)([2H])[2H]
description:
25,26,26,26,27,27-hexadeuterocholest-5-ene-3β,27-diol
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 1 mg (700059P-1mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC[C@@]([2H])(C([2H])([2H])[2H])C(O)([2H])[2H]
description: __
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packaging: __
manufacturer/tradename: Novagen®
shipped in: __
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SMILES string: __
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pkg of 1 × 10 mg (700060P-10mg)pkg of 1 × 5 mg (700060P-5mg)
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cholest-5-ene-3β,24(S)-diol
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>99% (TLC)
form:
powder
packaging:
pkg of 1 × 1 mg (700061P-1mg)pkg of 1 × 5 mg (700061P-5mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
__