700077P

FF-MAS

Manufacturer: Sigma Aldrich

CAS Number: 64284-64-6

Synonym(S): 14-demethyl-14-dehydrolanosterol, 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol; follicular fluid meiosis-activating sterol

Select a Size

Pack Size SKU Availability Price
1 MG 700077P-1-MG In Stock ₹ 1,02,339.55

700077P - 1 MG

₹ 1,02,339.55

In Stock

Quantity

1

Base Price: ₹ 1,02,339.55

GST (18%): ₹ 18,421.119

Total Price: ₹ 1,20,760.669

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700077P-1mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−70°C

InChI

1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1

InChI key

LFQXEZVYNCBVDO-PBJLWWPKSA-N

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Description

  • General description: Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in the cholesterol biosynthetic pathway present in all cells, and may represent the physiological signal that instructs the oocyte to reinitiate meiosis.
  • Application: FF-MAS has been used:as a standard in gas chromatography/ mass spectroscopy (GC/MS) for profiling sterols of oligodendrocyte progenitor cells (OPCs)[1]as Dulbecco′s modified eagle medium (DMEM) medium supplement to test its effect on cancer cell viability[2]to evaluate its effect on LXRβ-overexpressing squamous carcinoma SCC61 cells[3]
  • Biochem/physiol Actions: 14-demethyl-14-dehydrolanosterol (FF-MAS) was first identified in follicular fluid of women and plays a key role in oocyte nuclear maturation.[4] The levels of FF-MAS may be regulated by cytochrome P450 family 27 subfamily A member 1.[5] Supplementation of FF-MAS to oocytes promotes meiotic maturation favoring preimplantation. However, FF-MAS has low solubility and is metabolized to cholesterol rapidly.[6]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700077P-1mg)

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pkg of 1 × 1 mg (700077P-1mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
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−70°C

InChI:
1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1

InChI key:
LFQXEZVYNCBVDO-PBJLWWPKSA-N

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InChI key:
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InChI:
1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1

InChI key:
WQLVFSAGQJTQCK-VKROHFNGSA-N