78825

Liquiritigenin

≥97.0% (HPLC)

Manufacturer: Sigma Aldrich

Synonym(S): 7,4′-Dihydroxyflavanone, 7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one

Select a Size

Pack Size SKU Availability Price
10 MG 78825-10-MG In Stock ₹ 15,035.93
50 MG 78825-50-MG In Stock ₹ 48,290.33

78825 - 10 MG

₹ 15,035.93

In Stock

Quantity

1

Base Price: ₹ 15,035.93

GST (18%): ₹ 2,706.467

Total Price: ₹ 17,742.397

Quality Level

100

Assay

≥97.0% (HPLC)

form

powder or crystals

impurities

≤7% water

application(s)

metabolomicsvitamins, nutraceuticals, and natural products

SMILES string

Oc1ccc(cc1)[C@@H]2CC(=O)c3ccc(O)cc3O2

InChI

1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1

InChI key

FURUXTVZLHCCNA-AWEZNQCLSA-N

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Description

  • General description: Liquiritigenin is a flavonoid and an estrogenic compound found in licorice (Glycyrrhizae radix) root extract and several other plants.[1]
  • Application: Liquiritigenin has been used:to study its inhibitory effect on tumor metastasis in the treatment of colorectal cancer[2]as a reference standard for ultra-performance liquid chromatography (UPLC) of Chaihu-Shugan-San (CSS) extract[3]as a potential antiviral drug against hepatitis C virus (HCV) infection[4]
  • Biochem/physiol Actions: Liquiritigenin displays anti-diabetic[1] and choleretic[5] properties. It exerts anti-inflammatory activity on Raw246.7 cells by inhibiting nuclear factor kappa light chain enhancer of activated B cells (NF-κB)-dependent-induction of inducible NOS (iNOS).[6] Liquiritigenin inhibits liver fibrogenesis by blocking Hippo/Yes-associated protein (YAP) and transforming growth factor-β1 (TGF-β1)/small mothers against decapentaplegic (Smad) components.[7] It is a selective estrogen receptor β agonist[8] cells.[9] Liquiritigenin induces apoptosis in SMM-721 cells by disruption of the mitochondrial membrane potential and increased production of reactive oxygen species.[10]
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Oc1ccc(cc1)[C@@H]2CC(=O)c3ccc(O)cc3O2

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1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1

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FURUXTVZLHCCNA-AWEZNQCLSA-N

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1S/C7H15O10P/c8-1-3(9)5(11)7(13)6(12)4(10)2-17-18(14,15)16/h4-8,10-13H,1-2H2,(H2,14,15,16)/t4-,5-,6-,7+/m1/s1

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JDTUMPKOJBQPKX-GBNDHIKLSA-N

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