857228P

C18 LPA

Manufacturer: Sigma Aldrich

CAS Number: 799279-67-7

Synonym(S): 1-octadecyl-sn-glycero-3-phosphate (ammonium salt); PA(18:0e/0:0)

Select a Size

Pack Size SKU Availability Price
1 MG 857228P-1-MG In Stock ₹ 29,638.85

857228P - 1 MG

₹ 29,638.85

In Stock

Quantity

1

Base Price: ₹ 29,638.85

GST (18%): ₹ 5,334.993

Total Price: ₹ 34,973.843

Assay

>99% (LPA; may contain up to 10% of the 2-LPA isomer)

form

powder

packaging

pkg of 1 × 1 mg (857228P-1mg)

manufacturer/tradename

Avanti Polar Lipids 857228P

lipid type

phospholipidscardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(O)=O)([H])COCCCCCCCCCCCCCCCCCC.[NH4+]

Other Options

Image Product Name Manufacturer Price Range
AR00G7MX
1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (ammonium salt)
Aaron Chemicals LLC ₹ 37,133.04

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Description

  • General description: Lysophosphatidic acid (LPA) is a class of phospholipids,[1] which is water-soluble.[2] It has a glycerol backbone attached via a phosphate group, an aliphatic chain and a hydroxyl group. The aliphatic chain is linked to either sn-1 or sn-2 position and the phosphate group is connected to the sn-3 position. The hydroxyl group is linked to the remaining sn-1 or sn-2 position.[1]
  • Application: C18 LPA or 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate may be used: to study its effects on Yes-associated protein (YAP) phosphorylation [2] as a standard for the quantification of lysophosphatidic acid (LPA) compounds in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS)[3] as a substrate to investigate the phosphatase activity of soluble epoxide hydrolase (sEH) towards LPA compounds[1]
  • Biochem/physiol Actions: Lysophosphatidic acid (LPA) is a signaling molecule and alters various cellular responses through G protein-coupled receptors (GPCRs).[2] It stimulates smooth muscle contraction, cytoskeleton rearrangement and chemotaxis. LPA is also involved in inducing neurotransmitter release, cell proliferation, platelet aggregation and Ca2+ mobilization. Increased levels of LPA in human plasma leads to ovarian cancer and atherosclerosis. LPA acts as a potential biomarker for ovarian cancer.[1]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (857228P-1mg)

SAFETY INFORMATION

WGK

WGK 3

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Sigma Aldrich

857228P

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Assay:
>99% (LPA; may contain up to 10% of the 2-LPA isomer)

form:
powder

packaging:
pkg of 1 × 1 mg (857228P-1mg)

manufacturer/tradename:
Avanti Polar Lipids 857228P

lipid type:
phospholipidscardiolipins

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
O[C@](COP([O-])(O)=O)([H])COCCCCCCCCCCCCCCCCCC.[NH4+]

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Sigma Aldrich

857230P

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Assay:
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (857230P-1mg)

manufacturer/tradename:
Avanti Polar Lipids 857230P

lipid type:
cardiolipinsphospholipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
O[C@](COP([O-])(O)=O)([H])COCCCCCCCC/C=C\CCCCCCCC.[NH4+]

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manufacturer/tradename:
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lipid type:
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shipped in:
dry ice

storage temp.:
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SMILES string:
CCCCCCCC/C=C\CCCCCCCCOC[C@@H]1COP(O1)([O-])=O.[NH4+]

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manufacturer/tradename:
Avanti Polar Lipids

lipid type:
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shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[NH4+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP(O)([O-])=S)OC