860493P
1-deoxysphinganine
Manufacturer: Sigma Aldrich
CAS Number: 196497-48-0
Synonym(S): 1-deoxysphinganine (m18:0)
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 860493P-1-MG | In Stock | ₹ 32,096.13 |
| 10 MG | 860493P-10-MG | In Stock | ₹ 1,28,362.85 |
860493P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 32,096.13
GST (18%): ₹ 5,777.303
Total Price: ₹ 37,873.433
form
powder
packaging
pkg of 1 × 1 mg (860493P-1mg)pkg of 1 × 10 mg (860493P-10mg)
manufacturer/tradename
Avanti Polar Lipids 860493P
lipid type
bioactive lipidssphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
C[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
InChI
1S/C18H39NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17(2)19/h17-18,20H,3-16,19H2,1-2H3/t17-,18+/m0/s1
InChI key
YRYJJIXWWQLGGV-ZWKOTPCHSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Spisulosine | ChemScene | ₹ 23,443.44 | |
 | 196497-48-0 | (2S,3R)-2-Aminooctadecan-3-ol | A2B Chem | ₹ 9,069.36 - ₹ 71,100.36 |
Related Products
Description
- General description: 1-deoxysphinganine is synthesized by the condensation of palmitic acid with alanine or glycine in the presence of enzyme serine palmitoyltransferase (SPT).[1] It is metabolized to 1-deoxyceramides.[2]
- Application: 1-deoxysphinganine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing in MN9D dopaminergic neuroblastoma cell line.[3] It is also suitable for use as a neurotoxic agent in human CD8+ T cells.[4]
- Biochem/physiol Actions: 1-deoxysphinganine elicits cytotoxicity towards dorsal root ganglion (DRG) neurons by disrupting the neuronal cytoskeleton formation.[3] High levels of 1-deoxysphinganine in diabetic patients may contribute to the reduction of pancreatic β cell functionality.[1] In hereditary sensory and autonomic neuropathy type I, mutation in the serine palmitoyltransferase gene results in altered substrate specificity, resulting in the accumulation of 1-deoxysphinganine.[4]
- Packaging: 5 mL Amber Glass Screw Cap Vial (860493P-10mg)
Compare Similar Items
Show Difference
form: powder
packaging: pkg of 1 × 1 mg (860493P-1mg)pkg of 1 × 10 mg (860493P-10mg)
manufacturer/tradename: Avanti Polar Lipids 860493P
lipid type: bioactive lipidssphingolipids
shipped in: dry ice
storage temp.: −20°C
SMILES string: C[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
InChI: 1S/C18H39NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17(2)19/h17-18,20H,3-16,19H2,1-2H3/t17-,18+/m0/s1
InChI key: YRYJJIXWWQLGGV-ZWKOTPCHSA-N
form:
powder
packaging:
pkg of 1 × 1 mg (860493P-1mg)pkg of 1 × 10 mg (860493P-10mg)
manufacturer/tradename:
Avanti Polar Lipids 860493P
lipid type:
bioactive lipidssphingolipids
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
C[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
InChI:
1S/C18H39NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17(2)19/h17-18,20H,3-16,19H2,1-2H3/t17-,18+/m0/s1
InChI key:
YRYJJIXWWQLGGV-ZWKOTPCHSA-N
form: powder
packaging: pkg of 1 × 5 mg (860495P-5mg)
manufacturer/tradename: Avanti Polar Lipids 860495P
lipid type: deuterated lipidssphingolipids
shipped in: dry ice
storage temp.: −20°C
SMILES string: OC[C@@](NC)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI: __
InChI key: __
form:
powder
packaging:
pkg of 1 × 5 mg (860495P-5mg)
manufacturer/tradename:
Avanti Polar Lipids 860495P
lipid type:
deuterated lipidssphingolipids
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
OC[C@@](NC)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI:
__
InChI key:
__
form: powder
packaging: pkg of 1 × 200 mg (860499P-200mg)pkg of 1 × 25 mg (860499P-25mg)
manufacturer/tradename: Avanti Polar Lipids 860499P
lipid type: sphingolipids
shipped in: dry ice
storage temp.: −20°C
SMILES string: O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@](N)([H])CO
InChI: 1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChI key: AERBNCYCJBRYDG-KSZLIROESA-N
form:
powder
packaging:
pkg of 1 × 200 mg (860499P-200mg)pkg of 1 × 25 mg (860499P-25mg)
manufacturer/tradename:
Avanti Polar Lipids 860499P
lipid type:
sphingolipids
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@](N)([H])CO
InChI:
1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChI key:
AERBNCYCJBRYDG-KSZLIROESA-N
form: chloroform solution
packaging: package of 1 × 250 μg
manufacturer/tradename: Avanti Polar Lipids
lipid type: __
shipped in: dry ice
storage temp.: −20°C
SMILES string: __
InChI: __
InChI key: __
form:
chloroform solution
packaging:
package of 1 × 250 μg
manufacturer/tradename:
Avanti Polar Lipids
lipid type:
__
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
__
InChI:
__
InChI key:
__