860518P

C18 Ceramide (d18:1/18:0)

Manufacturer: Sigma Aldrich

CAS Number: 2304-81-6

Synonym(S): N-stearoyl-D-erythro-sphingosine

Select a Size

Pack Size SKU Availability Price
5 MG 860518P-5-MG In Stock ₹ 11,073.98
10 MG 860518P-10-MG In Stock ₹ 20,805.65

860518P - 5 MG

₹ 11,073.98

In Stock

Quantity

1

Base Price: ₹ 11,073.98

GST (18%): ₹ 1,993.316

Total Price: ₹ 13,067.296

form

powder

packaging

pkg of 1 × 10 mg (860518P-10mg)pkg of 1 × 5 mg (860518P-5mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C36H71NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,34-35,38-39H,3-28,30,32-33H2,1-2H3,(H,37,40)/b31-29+/t34-,35+/m0/s1

InChI key

VODZWWMEJITOND-NXCSZAMKSA-N

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Description

  • General description: C18 Ceramide (d18:1/18:0) synthesis is catalyzed by ceramide synthase (CERS) 1 and 5. It is a component of cellular membrane and has low gel forming ability compared to unsaturated ceramide.[1]
  • Application: C18 Ceramide (d18:1/18:0) has been used:to induce apoptosis in Manduca embryonic cell line (MRRL-CH1)[2]as a standard to quantify ceramide from liver tissue using liquid chromatography-mass spectrometry[3]to inhibit ceramidase in human embryonic kidney cells (HEK29) with β-glucocerebrosidase (GCase) mutation[4]
  • Biochem/physiol Actions: C18 Ceramide based derivatives are present in low levels during neurodegeneration. It favors endoplasmic reticulum based stress and autophagy in glioma cells.[5] Low levels of C18-ceramide are implicated in human head and neck squamous cell carcinoma. C18 ceramide may inhibit tumor progression.[6]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860518P-10mg)

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

860518P

--


form:
powder

packaging:
pkg of 1 × 10 mg (860518P-10mg)pkg of 1 × 5 mg (860518P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI:
1S/C36H71NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,34-35,38-39H,3-28,30,32-33H2,1-2H3,(H,37,40)/b31-29+/t34-,35+/m0/s1

InChI key:
VODZWWMEJITOND-NXCSZAMKSA-N

Img

Sigma Aldrich

860519P

--


form:
powder

packaging:
pkg of 1 × 25 mg (860519P-25mg)pkg of 1 × 5 mg (860519P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860519P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
OC[C@]([H])(NC(CCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI:
1S/C36H69NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,29,31,34-35,38-39H,3-16,19-28,30,32-33H2,1-2H3,(H,37,40)/b18-17-,31-29+/t34-,35+/m0/s1

InChI key:
OBFSLMQLPNKVRW-RHPAUOISSA-N

Img

Sigma Aldrich

860520P

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form:
powder

packaging:
pkg of 1 × 5 mg (860520P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860520P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI:
1S/C38H75NO3/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32-34-38(42)39-36(35-40)37(41)33-31-29-27-25-23-21-16-14-12-10-8-6-4-2/h31,33,36-37,40-41H,3-30,32,34-35H2,1-2H3,(H,39,42)/b33-31+/t36-,37+/m0/s1

InChI key:
XWBWIAOWSABHFI-NUKVNZTCSA-N

Img

Sigma Aldrich

860521P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860521P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860521P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O

InChI:
1S/C40H77NO8/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(43)33(32-48-40-39(47)38(46)37(45)35(31-42)49-40)41-36(44)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,33-35,37-40,42-43,45-47H,3-26,28,30-32H2,1-2H3,(H,41,44)/b29-27+/t33?,34-,35-,37+,38+,39-,40+/m1/s1

InChI key:
VJLLLMIZEJJZTE-BUDJNAOESA-N