860541P

C8 Lactosyl(β) Ceramide (d18:1/8:0)

Manufacturer: Sigma Aldrich

CAS Number: 384842-72-2

Synonym(S): D-lactosyl-β-1,1′ N-octanoyl-D-erythro-sphingosine

Select a Size

Pack Size SKU Availability Price
5 MG 860541P-5-MG In Stock ₹ 29,638.85

860541P - 5 MG

₹ 29,638.85

In Stock

Quantity

1

Base Price: ₹ 29,638.85

GST (18%): ₹ 5,334.993

Total Price: ₹ 34,973.843

form

powder

packaging

pkg of 1 × 5 mg (860541P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860541P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI

1S/C38H71NO13/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-27(42)26(39-30(43)22-20-17-8-6-4-2)25-49-37-35(48)33(46)36(29(24-41)51-37)52-38-34(47)32(45)31(44)28(23-40)50-38/h19,21,26-29,31-38,40-42,44-48H,3-18,20,22-25H2,1-2H3,(H,39,43)/b21-19+/t26-,27+,28?,29?,31-,32?,33?,34?,35?,36+,37+,38-/m0/s1

InChI key

JUCWRRXMPGRQOG-WKSBFREFSA-N

Other Options

Image Product Name Manufacturer Price Range
CS-0865275
LacCer d18:1/8:0
ChemScene --
AF83745
384842-72-2 | D-lactosyl--1,1' N-octanoyl-D-erythro-sphingosine
A2B Chem ₹ 1,00,875.24

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Description

  • General description: Lactosyl-ceramide is synthesized from complex glycosphingolipids by glucosylceramide synthase via caremide intermediate glucosylceramide.[1]
  • Application: C8 Lactosyl(β) Ceramide (d18:1/8:0) is suitable for use as a substrate for endoglycoceramidase II.[2] It is also suitable for use as a synthetic lipid standard for two-dimensional liquid chromatography−quadrupole time-of-flight mass spectrometry for lipid profiling[3] and lipidomic analysis.[4]
  • Biochem/physiol Actions: Lactosyl-β1-1′-N-octanoyl-D-erythro-sphingosine like other glycosphingolipids, stimulates caveolar endocytosis.[5] C8-LacCer mediates clustering of β1-integrins and actin cytoskeleton reorganization in skin fibroblasts.[6] High levels of lactosyl ceramide leads to decreased respiration leading to mitochondrial dysfunction.[1]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860541P-5mg)

SAFETY INFORMATION

WGK

WGK 3

Compare Similar Items

Show Difference

Img

Sigma Aldrich

860541P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860541P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860541P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI:
1S/C38H71NO13/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-27(42)26(39-30(43)22-20-17-8-6-4-2)25-49-37-35(48)33(46)36(29(24-41)51-37)52-38-34(47)32(45)31(44)28(23-40)50-38/h19,21,26-29,31-38,40-42,44-48H,3-18,20,22-25H2,1-2H3,(H,39,43)/b21-19+/t26-,27+,28?,29?,31-,32?,33?,34?,35?,36+,37+,38-/m0/s1

InChI key:
JUCWRRXMPGRQOG-WKSBFREFSA-N

Img

Sigma Aldrich

860545P

--


form:
powder

packaging:
pkg of 1 × 25 mg (860545P-25mg)pkg of 1 × 5 mg (860545P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860545P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI:
1S/C42H79NO13/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-31(46)30(43-34(47)26-24-22-20-17-12-10-8-6-4-2)29-53-41-39(52)37(50)40(33(28-45)55-41)56-42-38(51)36(49)35(48)32(27-44)54-42/h23,25,30-33,35-42,44-46,48-52H,3-22,24,26-29H2,1-2H3,(H,43,47)/b25-23+/t30-,31+,32?,33?,35-,36?,37?,38?,39?,40+,41+,42-/m0/s1

InChI key:
KNWHKVBHCLQVFX-NKNVVQMUSA-N

Img

Sigma Aldrich

860546P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860546P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860546P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O

InChI:
1S/C48H91NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(40-56-48-47(55)46(54)45(53)43(39-50)57-48)42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,41-43,45-48,50-51,53-55H,3-16,19-34,36,38-40H2,1-2H3,(H,49,52)/b18-17-,37-35+/t41?,42-,43-,45+,46+,47-,48+/m1/s1

InChI key:
WBOZIXHPUPAOIA-KVGFKTOYSA-N

Img

Sigma Aldrich

860547P

--


form:
powder

packaging:
pkg of 1 × 100 mg (860547P-100mg)pkg of 1 × 25 mg (860547P-25mg)pkg of 1 × 5 mg (860547P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

InChI:
1S/C42H81NO8/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-38(46)43-35(34-50-42-41(49)40(48)39(47)37(33-44)51-42)36(45)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,35-37,39-42,44-45,47-49H,3-28,30,32-34H2,1-2H3,(H,43,46)/b31-29+/t35-,36+,37?,39+,40?,41?,42+/m0/s1

InChI key:
YMYQEDCYNANIPI-KNSMPFANSA-N