860658P

sphinganine-d7

Manufacturer: Sigma Aldrich

CAS Number: 1246304-35-7

Synonym(S): D-erythro-sphinganine-d7

Select a Size

Pack Size SKU Availability Price
1 MG 860658P-1-MG In Stock ₹ 32,096.13

860658P - 1 MG

₹ 32,096.13

In Stock

Quantity

1

Base Price: ₹ 32,096.13

GST (18%): ₹ 5,777.303

Total Price: ₹ 37,873.433

form

powder

packaging

pkg of 1 × 1 mg (860658P-1mg)

manufacturer/tradename

Avanti Polar Lipids 860658P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@@](N)([H])[C@@](O)([H])CCCCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]

Other Options

Image Product Name Manufacturer Price Range
1246304-35-7 | D-erythro-sphinganine-d7
-- ₹ 19,046.00

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Description

  • General description: Sphinganine-d7 is a deuterated derivative of sphinganine. Sphinganine, also called as dihydrosphingosine is a derivative of sphingosine.[1] Sphinganines are produced in endoplasmic reticulum, by decarboxylating condensation of palmitoyl-CoA and serine.[2][3]
  • Application: Sphinganine-d7 has been used as an internal standard for quantification of sphingolipid concentrations in plasma[4] and tissue samples by high-performance liquid chromatography tandem mass spectrometry.[4][5][6]
  • Biochem/physiol Actions: Sphinganine (SPA) acts as a selective inhibitor of protein kinase C in intact human neutrophils.[1] It may function a potential biomarker for the diagnosis of sphingolipidoses.[2] SPA accumulation enables fumonisin B1 to stimulate apoptosis.[7] It also has an ability to block cholesterol transport in Niemann-Pick Type C (NPC) disease.[8]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860658P-1mg)