860665P

4E,14Z-Sphingadiene

Manufacturer: Sigma Aldrich

CAS Number: 25696-03-1

Synonym(S): (2S,3R,4E,14Z)-2-aminooctadec-4,14-diene-1,3-diol

Select a Size

Pack Size SKU Availability Price
1 MG 860665P-1-MG In Stock ₹ 32,096.13

860665P - 1 MG

₹ 32,096.13

In Stock

Quantity

1

Base Price: ₹ 32,096.13

GST (18%): ₹ 5,777.303

Total Price: ₹ 37,873.433

form

powder

packaging

pkg of 1 × 1 mg (860665P-1mg)

manufacturer/tradename

Avanti Polar Lipids 860665P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCC/C=C\CCC

InChI

1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h4-5,14-15,17-18,20-21H,2-3,6-13,16,19H2,1H3/b5-4-,15-14+

InChI key

KWDXKYNWAKMLKK-YQMRQDNGSA-N

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Description

  • General description: 4E,14Z-Sphingadiene is a unique sphingoid base containing C18 chain, with trans double bond at C-4 and cis double bond between C14 and C15 with a bent structure.[1][2] It is found in the plasma, lymph, brain, kidney and lungs of humans and mice.[1] 4E,14Z-Sphingadiene or d-erythro-1,3-dihydroxy-2-amino-4-trans-14-cis-octadecadiene is the second largest long-chain base of human plasma sphingomyelins.[2]
  • Biochem/physiol Actions: Sphingadiene, a vital component of sphingolipids facilitates numerous processes such as apoptosis and cell signaling.[3] It inhibits Akt/Wnt signaling and acts as an anticancer agent in colon cancer. [3][4]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860665P-1mg)

SAFETY INFORMATION

WGK

WGK 3