860815P

16:0(2R-OH) Ceramide

Manufacturer: Sigma Aldrich

CAS Number: 34839-02-6

Synonym(S): N-(2′-(R)-hydroxypalmitoyl)-D-erythro-sphingosine

Select a Size

Pack Size SKU Availability Price
5 MG 860815P-5-MG In Stock ₹ 38,970.00

860815P - 5 MG

₹ 38,970.00

In Stock

Quantity

1

Base Price: ₹ 38,970.00

GST (18%): ₹ 7,014.60

Total Price: ₹ 45,984.60

form

powder

packaging

pkg of 1 × 25 mg (860815P-25mg)pkg of 1 × 5 mg (860815P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860815P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCC)=O)CO

Other Options

Image Product Name Manufacturer Price Range
BL07874
34839-02-6 | N-(2'-(R)-hydroxypalmitoyl)-D-erythro-sphingosine
A2B Chem ₹ 1,19,869.56

Related Products

Img

Sigma Aldrich

860816P

--

Img

Sigma Aldrich

860830P

--

Img

Sigma Aldrich

860829P

--

Img

Sigma Aldrich

860827P

--

Img

Sigma Aldrich

860823P

--

Img

Sigma Aldrich

860821P

--

Img

Sigma Aldrich

860848P

--

Img

Sigma Aldrich

860828P

--

Description

  • General description: Ceramides with 2-hydroxy fatty acids (hFA) group are present in the epidermis.[1] 16:0(2R-OH) Ceramide is a unique ceramide containing 16C long chain base fatty acid (palmitic acid)-with 2′-hydroxyl group in R configuration.[2]
  • Biochem/physiol Actions: Hydroxy fatty acid (hFA)-sphingolipids are implicated in cell signaling.[3] They may also help in regulation of cell differentiation and apoptosis. Synthetic 2′R-hydroxy-C16-ceramide exhibits high proapoptotic activity than proapoptotic 2′S-hydroxy-C16-ceramide.[2] hFA-ceramides in epidermis support permeability barrier function. hFA-ceramides are synthesized by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H causes neurological disorders including, leukodystrophy and spastic paraparesis in humans.[3] The mechanism of action for an antitumor drug, PM02734 involves hFA-ceramides in the cell membrane.[4]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860815P-25mg)

SAFETY INFORMATION

WGK

WGK 3

Compare Similar Items

Show Difference

Img

Sigma Aldrich

860815P

--


form:
powder

packaging:
pkg of 1 × 25 mg (860815P-25mg)pkg of 1 × 5 mg (860815P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860815P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCC)=O)CO

Img

Sigma Aldrich

860816P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860816P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860816P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCC)=O)CO

Img

Sigma Aldrich

860817P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860817P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860817P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCC)=O)CO

Img

Sigma Aldrich

860818P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860818P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860818P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCCC)=O)CO