A2647

Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate

≥93% (HPLC), powder

Manufacturer: Sigma Aldrich

CAS Number: 25612-73-1

Synonym(S): β,γ-Imidoadenosine 5′-triphosphate lithium salt hydrate, AMP-PNP, ATP[β,γ-NH], Adenylyl imidodiphosphate lithium salt hydrate, App(NH)p

Select a Size

Pack Size SKU Availability Price
5 MG A2647-5-MG In Stock ₹ 10,543.55
25 MG A2647-25-MG In Stock ₹ 34,477.63
100 MG A2647-100-MG In Stock ₹ 1,12,872.28

A2647 - 5 MG

₹ 10,543.55

In Stock

Quantity

1

Base Price: ₹ 10,543.55

GST (18%): ₹ 1,897.839

Total Price: ₹ 12,441.389

biological source

natural (organic)

Quality Level

200

Assay

≥93% (HPLC)

form

powder

color

white

solubility

H2O: 50 mg/mL

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Li+].[Li+].[Li+].[Li+].[H]O[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)NP([O-])([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H17N6O12P3/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23)/t4-,6-,7-,10-/m1/s1

Other Options

Image Product Name Manufacturer Price Range
NC1366768
Sigma Aldrich Fine Chemicals Biosciences AMP-PNP | 25612-73-1 | 25 mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 25,993.13
50-186-5637
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5'-(beta,gamma-imido)triphosphate lithium salt hydrate >=93% (HPLC), powder | 25612-73-1 (free acid) | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 11,319.59
50-186-5635
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5'-(beta,gamma-imido)triphosphate lithium salt hydrate >=93% (HPLC), powder | 25612-73-1 (free acid) | 100MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 1,27,210.61
AR00BL4I
Adenylyl Imidodiphosphate
Aaron Chemicals LLC ₹ 7,358.16 - ₹ 2,30,241.96
AF39494
25612-73-1 | Adenylyl Imidodiphosphate
A2B Chem ₹ 7,871.52 - ₹ 2,00,039.28

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Description

  • Application: Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate has been used in a study to research the effects of monovalent cations Li+, Na+, K+, NH4+, Rb+ and Cs+ on the solid and solution structures of the nucleic acid components. Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate has also been used in a study to determine that antidepressants inhibit interferon-γ-induced microglial production of IL-6 and nitric oxide.
  • Biochem/physiol Actions: A non-hydrolyzable ATP analog. AMP-PNP competitively inhibits ATP-dependent enzyme systems, such as glutamine synthetase. It inhibits a number of enzymes which require the hydrolysis of ATP such as DNA topoisomerase II, SV40 large T-antigen helicase and a number of kinases. Blocks ATP-sensitive calcium-dependent potassium channels.
  • Caution: AMP-PNP is very unstable in acidic conditions; rapidly hydrolyzes to the phosphoramidate and inorganic phosphate.
  • Reconstitution: A 10 mg/mL stock solution may be made, aliquoted and stored at -70 °C for up to 3 months.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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[Li+].[Li+].[Li+].[Li+].[H]O[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)NP([O-])([O-])=O)[C@@H](O)[C@H]3O

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