Description

• General description: Deoxycholic acid sodium salt, also known as Sodium Deoxycholate, is a highly versatile ionic detergent utilized for its exceptional ability to solubilize membrane-bound proteins and lyse cells. Its mechanism involves disrupting cell membranes and dissolving hydrophobic molecules, making it an invaluable reagent in scientific research applications. In protein research, it plays a pivotal role in solubilizing proteins, particularly those embedded in membranes, enabling their extraction, purification, and subsequent analysis.Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.
• Application: Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue.[1] It has been used in the decellularization of aortic valvular conduit.[2]
• Biochem/physiol Actions: Solubilizes fats for absorption in the intestines.
• Features and Benefits: Highly versatile surfactant for your cell biology and biochemical research
• Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research