Description

• Application: Ethylenediaminetetraacetic acid has been used:as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation[1]as a medium component in the hepatic stellate cell (HSCs) culture[2]as a component of homogenization buffer for protein extraction from eye tissues[3]for stopping benzonase reaction in lysis buffer[4]
• Biochem/physiol Actions: Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples.[5] EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia.[6] EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection.[5] EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis.[7] Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.[8]