E9530

Erythropoietin from mouse

recombinant, expressed in NSO cells, ≥90% (SDS-PAGE), lyophilized powder, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): EPO

Select a Size

Pack Size SKU Availability Price
10 μG E9530-10-μG In Stock ₹ 67,909.80

E9530 - 10 μG

₹ 67,909.80

In Stock

Quantity

1

Base Price: ₹ 67,909.80

GST (18%): ₹ 12,223.764

Total Price: ₹ 80,133.564

biological source

mouse

Quality Level

200

recombinant

expressed in NSO cells

Assay

≥90% (SDS-PAGE)

form

lyophilized powder

potency

1.030 ng/mL

mol wt

~36 kDa by SDS-PAGEpredicted mol wt 18.6 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

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Description

  • General description: EPO (erythropoietin) gene is localized to human chromosome 7q22. This protein is predominantly produced by the cortex cells of kidney, as well as a variety of tissues including female reproductive organs.[1] It is a glycoprotein, which has a molecular weight of 34kDa. It is produced as a 193-amino acid precursor protein, which is cleaved to produce a secreted protein of 166-amino acid.[2]
  • Biochem/physiol Actions: EPO (erythropoietin) plays an essential role in the growth and differentiation of erythrocyte progenitor cells. It is involved in the pathogenesis of myomatous erythrocytosis syndrome, which is characterized by erythrocytosis and myomatous uterus.[1] It acts as a ligand for a homodimer of EPO-receptor (Epo-R), which is localized to the surface of immature erythroid cells. This interaction leads to inhibition of apoptosis and facilitation of cell proliferation and differentiation to mature erythrocytes.[2]
  • Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.
  • Analysis Note: The biological acitivity is measured by its ability to stimulate cell proliferation using TF-1 cell line.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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biological source:
mouse

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200

recombinant:
expressed in NSO cells

Assay:
≥90% (SDS-PAGE)

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lyophilized powder

potency:
1.030 ng/mL

mol wt:
~36 kDa by SDS-PAGEpredicted mol wt 18.6 kDa

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pkg of 10 μg

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avoid repeated freeze/thaw cycles

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cell culture | mammalian: suitable

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