G211040

DMT-2′O-TBDMS-rG(ib) Phosphoramidite

configured for MerMade

Manufacturer: Sigma Aldrich

CAS Number: 147201-04-5

Synonym(S): N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-guanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

Select a Size

Pack Size SKU Availability Price
0.5 G G211040-0.5-G In Stock ₹ 11,723.48
5 G G211040-5-G In Stock ₹ 52,782.70
10 G G211040-10-G In Stock ₹ 1,13,586.73

G211040 - 0.5 G

₹ 11,723.48

In Stock

Quantity

1

Base Price: ₹ 11,723.48

GST (18%): ₹ 2,110.226

Total Price: ₹ 13,833.706

biological source

non-animal source (no BSE/TSE risk)

Quality Level

300

product line

Proligo Reagents

Assay

≥99% (31P-NMR)≥99.0% (reversed phase HPLC)

form

powder

technique(s)

oligo synthesis: suitable

impurities

≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤0.5% single Impurity (reversed phase HPLC)≤3% residual Solvent content

color

white to off-white

λ

conforms (UV/VIS Identity)

suitability

conforms to structure for H-NMRconforms to structure for LC-MS

Description

  • General description: RNA phosphoramidites, along with RNA CPG, and analogous to DNA synthesis support the synthesis of sequence-specific RNA oligonucleotides for RNA interference (RNAi) and can be used in target validation and other drug development techniques.Modern phosphoramidite-mediated synthesis has enabled routine high-yielding preparations of RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products, and cost-effectiveness.Key FeaturesIndustry-standard 2′O-TBDMS protective group Consistent lot-to-lot purity and performanceCompatible with deprotection methods based on methylamine or AMAStandard RNA phosphoramidites provide excellent coupling results whenused with ETT or BTT as an activator; best results are obtained withActivator 42®Capping with standard acetic anhydride capping reagent rather than withFast Deprotection Cap AManufactured under a certified ISO 9001 quality systemDMT-2′O-TBDMS-rG(ib) Phosphoramidite is configured for MerMade Synthesizers.

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable