DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt hydrate
≥90% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 103476-21-7
Synonym(S): HMG-CoA
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | H6132-5-MG | In Stock | ₹ 30,732.18 |
| 10 MG | H6132-10-MG | In Stock | ₹ 51,775.98 |
| 25 MG | H6132-25-MG | In Stock | ₹ 98,226.05 |
H6132 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 30,732.18
GST (18%): ₹ 5,531.792
Total Price: ₹ 36,263.972
Quality Level
200
Assay
≥90% (HPLC)
storage temp.
−20°C
SMILES string
O.[Na+].[Na+].CC(O)(CC(O)=O)CC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n2cnc3c(N)ncnc23
InChI
1S/C27H44N7O20P3S.2Na.H2O/c1-26(2,21(40)24(41)30-5-4-15(35)29-6-7-58-17(38)9-27(3,42)8-16(36)37)11-51-57(48,49)54-56(46,47)50-10-14-20(53-55(43,44)45)19(39)25(52-14)34-13-33-18-22(28)31-12-32-23(18)34;;;/h12-14,19-21,25,39-40,42H,4-11H2,1-3H3,(H,29,35)(H,30,41)(H,36,37)(H,46,47)(H,48,49)(H2,28,31,32)(H2,43,44,45);;;1H2/q;2*+1;/p-2/t14-,19-,20-,21-,25-,27?;;;/m1.../s1
InChI key
QGWMCHPRNDWWMT-UAUHQYJPSA-L
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate | ChemScene | ₹ 31,229.40 | |
 | 103476-21-7 | D,L-3-Hydroxy-3-methylglutaryl Coenzyme A trisodium salt | A2B Chem | ₹ 34,224.00 |
Related Products
Description
- General description: DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) is obtained from acetyl-CoA and acetoacetyl-CoA during condensation with the help of HMG-CoA synthase.[1]
- Application: DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt hydrate has been used in drug treatment to study its effect on mTORC1 regulation.[2] It has also been used to compare the acylomes of two reactive acyl-CoA species, like HMG-CoA and glutaryl-CoA.[3]
- Biochem/physiol Actions: DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) is a substrate used to study the specificity and kinetics of the enzyme 3-hydroxyl-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase. HMG-CoA is the key intermediate in the biosynthsis of terpenes and ketone bodies. Its metabolism is the target of statin drugs used to control cholesterol levels.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Quality Level: 200
Assay: ≥90% (HPLC)
storage temp.: −20°C
SMILES string: O.[Na+].[Na+].CC(O)(CC(O)=O)CC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n2cnc3c(N)ncnc23
InChI: 1S/C27H44N7O20P3S.2Na.H2O/c1-26(2,21(40)24(41)30-5-4-15(35)29-6-7-58-17(38)9-27(3,42)8-16(36)37)11-51-57(48,49)54-56(46,47)50-10-14-20(53-55(43,44)45)19(39)25(52-14)34-13-33-18-22(28)31-12-32-23(18)34;;;/h12-14,19-21,25,39-40,42H,4-11H2,1-3H3,(H,29,35)(H,30,41)(H,36,37)(H,46,47)(H,48,49)(H2,28,31,32)(H2,43,44,45);;;1H2/q;2*+1;/p-2/t14-,19-,20-,21-,25-,27?;;;/m1.../s1
InChI key: QGWMCHPRNDWWMT-UAUHQYJPSA-L
Quality Level: 500
Assay: __
storage temp.: 2-8°C
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Quality Level: 400
Assay: ≥99.5% (titration)
storage temp.: __
SMILES string: __
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