M5319

Matrine

Manufacturer: Sigma Aldrich

CAS Number: 519-02-8

Synonym(S): Matridin-15-one, Sophocarpidine

Select a Size

Pack Size SKU Availability Price
100 MG M5319-100-MG In Stock ₹ 30,732.18
500 MG M5319-500-MG In Stock ₹ 52,696.10

M5319 - 100 MG

₹ 30,732.18

In Stock

Quantity

1

Base Price: ₹ 30,732.18

GST (18%): ₹ 5,531.792

Total Price: ₹ 36,263.972

Quality Level

100

application(s)

metabolomicsvitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

O=C1CCCC2C3CCCN4CCCC(CN12)C34

InChI

1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1

InChI key

ZSBXGIUJOOQZMP-JLNYLFASSA-N

Other Options

Image Product Name Manufacturer Price Range
50-176-2736
Sigma Aldrich Fine Chemicals Biosciences Matrine | 519-02-8 | MFCD00210527 | 100MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 39,304.55
50-244-7987
eMolecules​ Medchem Express / Matrine / 100mg / 446274745 / HY-N0164 / / 519-02-8 / [null] / 248.370 / C15H24N2O
eMolecules​ ₹ 11,334.99
50-193-3438
Medchemexpress LLC HY-N0164 100mg Medchemexpress, Matrine CAS:519-02-8 Purity:>98%
Medchemexpress LLC ₹ 8,085.42
Y0002013
Matrine
Sigma Aldrich ₹ 17,536.50
PHL89730
Matrine
Sigma Aldrich ₹ 27,636.23
AR0038EX
(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
Aaron Chemicals LLC --
CS-1601
Matrine
ChemScene ₹ 13,689.60 - ₹ 47,742.48
AB49773
519-02-8 | (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
A2B Chem ₹ 1,112.28 - ₹ 43,892.28

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Description

  • General description: Matrine (MT) or Sophocarpidine is a naturally occurring bioactive compound, extracted from traditional Chinese herbs like Sophora flavescens and Radix Sophorae tonkinensis.[1]
  • Application: Matrine has been used:to study its antioxidant and protective effect on doxorubicin (DOX)-induced cardiotoxicity in mice model and H9C2 cells[2]as a chemotherapeutic agent to test its inhibitory effect on the growth of human glioblastoma multiforme (GBM) cells[3], and ovarian cancer cells[4]to study its effect on mitochondrial fission and its anti-tumor functionality in HepG2 cells[5]as a necroptosis inducer in cholangiocarcinoma (CCA) cell lines[6]
  • Biochem/physiol Actions: Matrine is a potent therapeutic agent with various pharmacological like anti-cancer, anti-bacterial, anti-fibrotic, anti-inflammatory properties.[1] It is a macropinocytosis inducer and decreases the cellular adenosine triphosphate (ATP) level.[7] Matrine may also serve as an effective sedative agent.[8] It serves as an anti-inflammatory agent in 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced intestinal inflammation in mice.[9] It functions to reverse the Warburg effect and suppress the growth of human colon cancer cells.[10]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1

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[H]O[H].OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@@]2(CO)O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@@H](O)[C@@H]1O

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