M9281
3-Methyladenine
autophagy inhibitor
Manufacturer: Sigma Aldrich
CAS Number: 5142-23-4
Synonym(S): 3-MA, 6-Amino-3-methylpurine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | M9281-100-MG | In Stock | ₹ 20,224.20 |
| 500 MG | M9281-500-MG | In Stock | ₹ 79,809.00 |
M9281 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 20,224.20
GST (18%): ₹ 3,640.356
Total Price: ₹ 23,864.556
biological source
synthetic (organic)
Quality Level
300
Assay
≥99% (HPLC)
form
powder
mp
~300 °C (dec.) (lit.)
solubility
DMF: 9.80-10.20 mg/mL, clear, colorless to light yellow
SMILES string
Cn1cnc(N)c2ncnc12
InChI
1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
InChI key
FSASIHFSFGAIJM-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MilliporeSigma™ Calbiochem™ Autophagy Inhibitor, 3-MA | Fischer Scientific | -- | |
| | MilliporeSigma™ Calbiochem™ Autophagy Inhibitor, 3-MA | Fischer Scientific | ₹ 13,367.04 | |
| | MilliporeSigma™ Calbiochem™ Autophagy Inhibitor, 3-MA | Fischer Scientific | ₹ 14,736.00 | |
 | Enzo Life Sciences 3-Methyladenine (25mg). CAS: 5142-23-4 | Enzo Life Sciences | ₹ 11,020.13 | |
 | AdipoGen 3-Methyladenine, 5142-23-4, MFCD00010531, 25 mg | AdipoGen | ₹ 3,593.52 | |
| | Sigma Aldrich Fine Chemicals Biosciences 3-Methyladenine autophagy inhibitor | 5142-23-4 | MFCD00010531 | 100MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 24,945.02 | |
 | AdipoGen 3-Methyladenine,Chemical. CAS: 5142-23-4 | AdipoGen | ₹ 4,620.24 | |
 | Selleck Chemical LLC 3-Methyladenine (3-MA) 50mg 5142-23-4 NSC 66389 | Selleck Chemical LLC | ₹ 15,092.78 | |
 | Cayman Chemical 3-Methyladenine, 5142-23-4, 25 mg | Cayman Chemical | ₹ 3,798.86 | |
 | Apexbio Technology LLC 3-Methyladenine, 5142-23-4, MFCD00010531, 50 mg | Apexbio Technology LLC | ₹ 4,534.68 |
Related Products
Description
- Application: 3-Methyladenine (3-MA) is used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor, 3-MA is typically used at a concentration of 5 mM.
- Biochem/physiol Actions: 3-Methyladenine (3-MA) is used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III phosphatidylinositol 3-kinases (PI-3K).[4]
- Preparation Note: This product is soluble in DMF (10 mg/mL; may require gentle heating). It is also soluble in water, 95% ethanol, or 1 N NaOH at 30 mg/mL with heating, but upon cooling, the product precipitates from solution. Solutions of 3-MA may be prepared in DMSO at 100 mM.
- Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
biological source: synthetic (organic)
Quality Level: 300
Assay: ≥99% (HPLC)
form: powder
mp: ~300 °C (dec.) (lit.)
solubility: DMF: 9.80-10.20 mg/mL, clear, colorless to light yellow
SMILES string: Cn1cnc(N)c2ncnc12
InChI: 1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
InChI key: FSASIHFSFGAIJM-UHFFFAOYSA-N
biological source:
synthetic (organic)
Quality Level:
300
Assay:
≥99% (HPLC)
form:
powder
mp:
~300 °C (dec.) (lit.)
solubility:
DMF: 9.80-10.20 mg/mL, clear, colorless to light yellow
SMILES string:
Cn1cnc(N)c2ncnc12
InChI:
1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
InChI key:
FSASIHFSFGAIJM-UHFFFAOYSA-N
biological source: __
Quality Level: 400
Assay: __
form: liquid
mp: __
solubility: __
SMILES string: __
InChI: __
InChI key: __
biological source:
__
Quality Level:
400
Assay:
__
form:
liquid
mp:
__
solubility:
__
SMILES string:
__
InChI:
__
InChI key:
__
biological source: __
Quality Level: 300
Assay: __
form: liquid
mp: __
solubility: __
SMILES string: __
InChI: __
InChI key: __
biological source:
__
Quality Level:
300
Assay:
__
form:
liquid
mp:
__
solubility:
__
SMILES string:
__
InChI:
__
InChI key:
__
biological source: __
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
mp: 273 °C
solubility: __
SMILES string: CSCC[C@@H](N)C(O)=O
InChI: 1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
InChI key: FFEARJCKVFRZRR-SCSAIBSYSA-N
biological source:
__
Quality Level:
200
Assay:
≥98% (HPLC)
form:
powder
mp:
273 °C
solubility:
__
SMILES string:
CSCC[C@@H](N)C(O)=O
InChI:
1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
InChI key:
FFEARJCKVFRZRR-SCSAIBSYSA-N