MAK521
Fumarase Assay Kit
sufficient for 100 colorimetric tests
Manufacturer: Sigma Aldrich
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KIT | MAK521-1-KIT | In Stock | ₹ 65,112.60 |
MAK521 - 1 KIT
In Stock
Quantity
1
Base Price: ₹ 65,112.60
GST (18%): ₹ 11,720.268
Total Price: ₹ 76,832.868
Quality Level
100
detection method
colorimetric
relevant disease(s)
neurological disorders; neonatal diseases
shipped in
wet ice
storage temp.
−20°C
Related Products
Description
- General description: Fumarase (or fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration reaction of fumarate to malate. Fumarase exists in two isoforms: a cytosolic and mitochondrial form. In the citric acid cycle, it facilitates a transition step in the production of energy in the form of NADH. Fumarase deficiency in humans results in early brain development problems and is characterized by poor feeding, hypotonia, failure to thrive, etc.
- Features and Benefits: Linear detection range: 0.4 to 70 U/LCompatible with high-throughput handling systems.
- Suitability: The kit is suitable for fumarase activity determination in biological samples (e.g. plasma, serum, erythrocytes, tissue and culture media.)
- Principle: The Fumarase Assay Kit is a non-radioactive, colorimetric assay based on the reduction of the tetrazolium salt MTT in a NADH-coupled enzymatic reaction to a reduced form of MTT which exhibits an absorption maximum at 565 nm. The increase in absorbance at 565 nm is proportional to the enzyme activity.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P210 - P233 - P234 - P240 - P303 + P361 + P353 - P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Central nervous system
WGK
WGK 3
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