Neomycin trisulfate salt hydrate
meets USP testing specifications, powder
Manufacturer: Sigma Aldrich
CAS Number: 1405-10-3
Synonym(S): Framycetin sulfate, Neomycin Sulfate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 G | N5285-25-G | In Stock | ₹ 7,945.55 |
| 100 G | N5285-100-G | In Stock | ₹ 18,532.40 |
N5285 - 25 G
In Stock
Quantity
1
Base Price: ₹ 7,945.55
GST (18%): ₹ 1,430.199
Total Price: ₹ 9,375.749
Agency
USP/NFmeets USP testing specifications
Quality Level
200
form
powder
solubility
H2O: 50 mg/mL (Stock solutions should be filter sterilized and stored at 2-8 °C. Stable at 37 °C for 5 days.)
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteria
application(s)
pharmaceutical (small molecule)
Mode of action
protein synthesis | interferes
SMILES string
O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)C(N)[C@@H](O)[C@@H]1O
InChI
1S/C23H46N6O13.3H2O4S.H2O/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;3*1-5(2,3)4;/h5-23,30-36H,1-4,24-29H2;3*(H2,1,2,3,4);1H2/t5-,6+,7-,8+,9-,10-,11?,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;;;;/m1..../s1
InChI key
WHAGUNPVKDUVFV-QGTTWHFQSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | TOKU-E Neomycin Sulfate, USP, 1405-10-3, 25 g | TOKU-E | ₹ 4,894.03 | |
 | TOKU-E Neomycin Sulfate, USP, 1405-10-3, 100 g | TOKU-E | ₹ 9,240.48 | |
 | TOKU-E Neomycin Sulfate, USP, 1405-10-3, 500 g | TOKU-E | ₹ 39,956.52 | |
 | Sigma Aldrich Fine Chemicals Biosciences Neomycin sulphate European Pharmacopoeia (EP) Reference Standard | 1405-10-3 | | Sigma Aldrich Fine Chemicals Biosciences | ₹ 23,582.90 | |
 | Enzo Life Sciences Neomycin . sulfate (25g). CAS: 1405-10-3 | Enzo Life Sciences | ₹ 44,474.09 | |
| | Neomycin sulfate | Sigma Aldrich | ₹ 47,987.23 | |
| | Neomycin sulfate, for microbiological assay | Sigma Aldrich | ₹ 16,107.60 | |
 | Neomycin trisulfate salt hydrate | Supelco | ₹ 2,673.78 | |
| | Neomycin trisulfate salt hydrate | Sigma Aldrich | ₹ 28,274.90 | |
| | Neomycin trisulfate salt hydrate | Sigma Aldrich | ₹ 3,734.63 - ₹ 23,230.45 |
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Description
- General description: Chemical structure: aminoglycoside
- Application: Neomycin Trisulfate is produced by Streptomyces containing a minimum of 85% neomycin B. It has been used as a selection agent for prokaryotic cells transformed using the neo selectable marker gene, and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins. It is recommended for use in cell culture applications at 50 mg/L.
- Biochem/physiol Actions: Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria.
- Caution: Stock solutions should be filter sterilized and stored at 2-8°C, and are stable at 37°C for 5 days. A 1 mg/mL neomycin solution in .1 M phosphate buffer, pH 8.0 should be used within 14 days when stored at 0-5°C. Solutions should be protected from light or moisture.
- Preparation Note: Neomycin sulfate is soluble in H2O at 50 mg/mL, yielding a clear solution.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Agency: USP/NFmeets USP testing specifications
Quality Level: 200
form: powder
solubility: H2O: 50 mg/mL (Stock solutions should be filter sterilized and stored at 2-8 °C. Stable at 37 °C for 5 days.)
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteria
application(s): pharmaceutical (small molecule)
Mode of action: protein synthesis | interferes
SMILES string: O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)C(N)[C@@H](O)[C@@H]1O
InChI: 1S/C23H46N6O13.3H2O4S.H2O/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;3*1-5(2,3)4;/h5-23,30-36H,1-4,24-29H2;3*(H2,1,2,3,4);1H2/t5-,6+,7-,8+,9-,10-,11?,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;;;;/m1..../s1
InChI key: WHAGUNPVKDUVFV-QGTTWHFQSA-N
Agency: __
Quality Level: __
form: __
solubility: __
antibiotic activity spectrum: __
application(s): __
Mode of action: __
SMILES string: __
InChI: __
InChI key: __
Agency: __
Quality Level: 200
form: powder
solubility: __
antibiotic activity spectrum: __
application(s): __
Mode of action: __
SMILES string: CCCCCCCCCCCCCCCCCCC(=O)OC
InChI: 1S/C20H40O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-2/h3-19H2,1-2H3
InChI key: __
