S9263

Swainsonine

solid, ≥99% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 72741-87-8

Synonym(S): (1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol

Select a Size

Pack Size SKU Availability Price
0.1 MG S9263-0.1-MG In Stock ₹ 20,480.90
0.5 MG S9263-0.5-MG In Stock ₹ 59,515.85

S9263 - 0.1 MG

₹ 20,480.90

In Stock

Quantity

1

Base Price: ₹ 20,480.90

GST (18%): ₹ 3,686.562

Total Price: ₹ 24,167.462

product name

Swainsonine, synthetic

biological source

synthetic

Quality Level

200

Assay

≥99% (HPLC)

form

solid

solubility

methanol: 5 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12

InChI

1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1

InChI key

FXUAIOOAOAVCGD-DCDLSZRSSA-N

Other Options

Image Product Name Manufacturer Price Range
50-201-1738
Enzo Life Sciences Swainsonine (5 mg). CAS: 72741-87-8
Enzo Life Sciences ₹ 81,548.95
50-197-0461
Medchemexpress LLC HY-N6722 1mg Medchemexpress, Swainsonine CAS:72741-87-8 Purity:>98%
Medchemexpress LLC ₹ 26,951.40
57-477-5500UG
MilliporeSigma™ Calbiochem™ Swainsonine, Swainsona canescens
MilliporeSigma™ ₹ 8,972.68
S8195
Swainsonine
Sigma Aldrich ₹ 29,043.48
S8195
Swainsonine
Sigma Aldrich ₹ 29,043.48
AC82813
72741-87-8 | Swainsonine
A2B Chem ₹ 7,785.96 - ₹ 56,469.60

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Description

  • General description: Swainsonine is produced by endophytes, plant and insect pathogens. It is synthesized from the pipecolic acid and mevalonic acid.[1] Swainsonine is a water-soluble indole alkaloid.[2]
  • Application: Swainsonine has been used:to test its effect on neural stem cell proliferation[2]to inhibit α-mannosidase in TC-1 tumor cells[3]to inhibit β1,6-branching synthesis in hepatocellular carcinoma (HCC) cells[4]
  • Biochem/physiol Actions: Swainsonine is an inhibitor of α-mannosidase in endoplasmic reticulum and Golgi apparatus. It also activates the natural killer cells.[3] Swainsonine elicits neurologic toxicity and its exposure impairs learning and memory resulting in cognitive deficit.[2] It inhibits hepatocellular carcinoma and sensitizes them to respond to anti-cancer drug paclitaxel.[5]

SAFETY INFORMATION

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sigma Aldrich

S9263

solid, ≥99% (HPLC)...


product name:
Swainsonine, synthetic

biological source:
synthetic

Quality Level:
200

Assay:
≥99% (HPLC)

form:
solid

solubility:
methanol: 5 mg/mL, clear, colorless to light yellow

storage temp.:
−20°C

SMILES string:
O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12

InChI:
1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1

InChI key:
FXUAIOOAOAVCGD-DCDLSZRSSA-N

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