V2753

Virginiamycin M1

≥95% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 21411-53-0

Synonym(S): Ostreogrycin A, Pristinamycin IIA, Staphylomycin M1, Streptogramin A, Virginiamycin M1, Mikamycin A, Staphylomycin

Select a Size

Pack Size SKU Availability Price
5 MG V2753-5-MG In Stock ₹ 54,503.88
10 MG V2753-10-MG In Stock ₹ 67,407.28

V2753 - 5 MG

₹ 54,503.88

In Stock

Quantity

1

Base Price: ₹ 54,503.88

GST (18%): ₹ 9,810.698

Total Price: ₹ 64,314.578

biological source

Streptomyces virginiae

Quality Level

200

Assay

≥95% (HPLC)

form

powder

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)

color

white to yellow

solubility

methanol: soluble 10 mg/mL

antibiotic activity spectrum

Gram-positive bacteria

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

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Description

  • General description: Chemical structure: macrolide
  • Application: The antibiotic virginiamycin is produced by Streptomyces virginiae and is a member of the virginiamycin family. Each member is produced as a mixture of two structurally different compounds that exhibit synergistic antibacterial activity. There are two groups: virginiamycin M1 (VM1) and virginiamycin S (VS). VM1 is a polyunsaturated macrocyclic petolide. VM1 and VS are both used to inhibit protein synthesis since they are bacteriostatic. When used in combination they are more effective. Virginiamycin is used as a performance promoter in animal husbandry. They are chemically modified to make therapeutic drugs such as quinupristin and dalfopristin[1].
  • Biochem/physiol Actions: Virginiamycin M1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. S. virginiae inactivates VM1 by reducing its 16-carbonyl group, forming 16R-dihydroVM1. VM1 reductase participates solely in VM1 inactivation in vivo[2].
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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white to yellow

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methanol: soluble 10 mg/mL

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Gram-positive bacteria

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protein synthesis | interferes

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