305995

2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite

97%

Manufacturer: Sigma Aldrich

CAS Number: 102691-36-1

Synonym(S): Bis(diisopropylamino)(2-cyanoethoxy)phosphine

Select a Size

Pack Size SKU Availability Price
1 G 305995-1-G In Stock ₹ 7,350.18
5 G 305995-5-G In Stock ₹ 17,363.30

305995 - 1 G

₹ 7,350.18

In Stock

Quantity

1

Base Price: ₹ 7,350.18

GST (18%): ₹ 1,323.032

Total Price: ₹ 8,673.212

Quality Level

200

Assay

97%

form

liquid

refractive index

n20/D 1.470 (lit.)

bp

100 °C/0.5 mmHg (lit.)

density

0.949 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

CC(C)N(C(C)C)P(OCCC#N)N(C(C)C)C(C)C

InChI

1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3

InChI key

RKVHNYJPIXOHRW-UHFFFAOYSA-N

Description

  • Application: 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite was used:in preparation of prosphoramidite reagent, required for synthesis of 12-mer oligodeoxynucleotide[1]as phosphorylating agent in synthesis of 1,2-diacyl-sn-glycerophosphatidylserine[2]in situ preparation of deoxyribonucleoside phosphoramidites[3]in preparation of 2′-deoxy-2′-fluoro-3′-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-5′-O-(4-methoxytrityl)-4′-thio-β-D-arabinouridine and 1-(3-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-2-deoxy-2-fluoro-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-arabinofuranosyl)-thymine[4]as reagent for synthesizing phosphitylated nucleotides[5]

SAFETY INFORMATION

Pictograms

GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H302,H317,H412

Precautionary Statements

P210 - P233 - P273 - P280 - P301 + P312 - P303 + P361 + P353

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 3 - Skin Sens. 1B

WGK

WGK 2

Flash Point(F)

119.3 °F

Flash Point(C)

48.5 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
200

Assay:
97%

form:
liquid

refractive index:
n20/D 1.470 (lit.)

bp:
100 °C/0.5 mmHg (lit.)

density:
0.949 g/mL at 25 °C (lit.)

storage temp.:
−20°C

SMILES string:
CC(C)N(C(C)C)P(OCCC#N)N(C(C)C)C(C)C

InChI:
1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3

InChI key:
RKVHNYJPIXOHRW-UHFFFAOYSA-N

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SMILES string:
O=C(OC1CCCCC1)c2ccccc2C(=O)OC3CCCCC3

InChI:
1S/C20H26O4/c21-19(23-15-9-3-1-4-10-15)17-13-7-8-14-18(17)20(22)24-16-11-5-2-6-12-16/h7-8,13-16H,1-6,9-12H2

InChI key:
VOWAEIGWURALJQ-UHFFFAOYSA-N