Description

• General description: Citric acid monohydrate is an organic acid. Its molar enthalpy of solution in water has been reported to be ΔsolHm (298.15K, m = 0.0203molkg-1) = (29061±123)Jmol-1.[1] It can be produced by crystallization from mother liquor of citric acid solution at 20-25°C during citric acid synthesis.[2] An investigation of its crystal growth kinetics indicates that growth is linearly dependent on size.[3]Citric acid monohydrate is an organic weak acid used as a natural preservative in food and beverage products.[4]
• Application: Citric acid monohydrate was used in the preparation of citric acid solution employed in the acetone method of 68Ga pre-purification and radiolabeling technique.[5]It may be used:As release-modifying agent to improve the release of diltiazem hydrochloride from melt extruded Eudragit RS PO tablets.[6] To prepare citrate buffer for use in the preparation of platelets for intravital microscopy.[7]To prepare Tris-citrate buffer employed for the electrophoresis of bacterial enzymes.[8]