07858

(R)-(−)-3-Amino-1-Boc-piperidine

≥98.0% (TLC)

Manufacturer: Sigma Aldrich

CAS Number: 188111-79-7

Synonym(S): (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate

Select a Size

Pack Size SKU Availability Price
1 G 07858-1-G In Stock ₹ 16,399.88

07858 - 1 G

₹ 16,399.88

In Stock

Quantity

1

Base Price: ₹ 16,399.88

GST (18%): ₹ 2,951.978

Total Price: ₹ 19,351.858

Quality Level

100

Assay

≥98.0% (TLC)

optical activity

[α]/D -28.5±2°, c = 1 in DMF

SMILES string

CC(C)(C)OC(=O)N1CCC[C@@H](N)C1

InChI

1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1

InChI key

AKQXKEBCONUWCL-MRVPVSSYSA-N

Other Options

Image Product Name Manufacturer Price Range
NC2187738
eMolecules​ (R)-1-Boc-3-Aminopiperidine | 188111-79-7 | MFCD03094717 | 10g
eMolecules​ ₹ 2,767.01
AR00333K
(R)-1-Boc-3-Aminopiperidine
Aaron Chemicals LLC ₹ 256.68 - ₹ 28,748.16
CS-W009040
(R)-1-Boc-3-aminopiperidine
ChemScene ₹ 941.16 - ₹ 71,442.60

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Description

  • General description: (R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.[1]
  • Application: (R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.[2]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Precautionary Statements

P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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07858

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Quality Level:
100

Assay:
≥98.0% (TLC)

optical activity:
[α]/D -28.5±2°, c = 1 in DMF

SMILES string:
CC(C)(C)OC(=O)N1CCC[C@@H](N)C1

InChI:
1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1

InChI key:
AKQXKEBCONUWCL-MRVPVSSYSA-N

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