Description

• General description: Tris(dibenzylideneacetone)dipalladium(0) (Pd2(dba)3) is a versatile compound widely used as a Pd(0) source in various Pd-mediated transformations.[1] Pd2(dba)3 is known for its high reactivity and ability to facilitate oxidative addition reactions. It is prepared by reacting palladium salts with dibenzylideneacetone ligands. It acts as a catalyst for several reactions including Suzuki cross-coupling, Heck coupling, arylation, Buchwald-Hartwig amination, and fluorination. It is often used in catalytic amounts and has been shown to be effective in promoting coupling reactions between aryl halides and boronic acids.[2]For small scale and high throughput uses, product is also available as ChemBeads (919772)
• Application: Application Guide for Palladium Catalyzed Cross-Coupling ReactionsReactant involved in: Synthesis of azepanes[3] Synthesis of nanosized palladium phosphides upon interaction with white phosphorous Preparation of palladium triphenylphosphine carbonyl cluster complexes Precursor for synthesis of functionalized multiwalled carbon nanotube-palladium complexes used as catalysts for Heck coupling reactions Selective carbon-sulfur bond formation via addition of S-S and S-H bonds to alkynesCatalyst for: Suzuki cross-coupling reactions PCN- and PCS-pincer palladium complex catalyzed tandem allylation Catalyst for Suzuki coupling of aryl chlorides[4] (eq. 1) Catalyst for Heck coupling of aryl chlorides[4] (eq. 2) Catalyst for arylation of ketones[5] (eq. 3) Catalyst for Buchwald-Hartwig amination of aryl halides[6] (eq. 4) Catalyst for fluorination of allylic chlorides[7] (eq. 5) Catalyst for β-arylation of carboxylic esters[8] (eq. 6) Catalyst for carbonylation of 1,1-dichloro-1-alkenes[9] (eq. 7) Catalyst for conversion of aryl and vinyl triflates to aryl and vinyl halides[10] (eq. 8) Pd source for enantioselective Tsuji Allylations[11][12]