368199

(S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol

99%

Manufacturer: Sigma Aldrich

CAS Number: 112068-01-6

Synonym(S): (S)-(−)-2-(Diphenylhydroxymethyl)pyrrolidine, α,α-Diphenyl-L-prolinol

Select a Size

Pack Size SKU Availability Price
1 G 368199-1-G In Stock ₹ 5,390.85
5 G 368199-5-G In Stock ₹ 17,471.55

368199 - 1 G

₹ 5,390.85

In Stock

Quantity

1

Base Price: ₹ 5,390.85

GST (18%): ₹ 970.353

Total Price: ₹ 6,361.203

Quality Level

200

Assay

99%

form

solid

optical activity

[α]20/D −67°, c = 3 in chloroform

mp

77-80 °C (lit.)

SMILES string

OC([C@@H]1CCCN1)(c2ccccc2)c3ccccc3

InChI

1S/C17H19NO/c19-17(16-12-7-13-18-16,14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16,18-19H,7,12-13H2/t16-/m0/s1

InChI key

OGCGXUGBDJGFFY-INIZCTEOSA-N

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Description

  • General description: (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol is a bifunctional organocatalyst.[1]
  • Application: (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol (DPPM) may be used in the following processes:DPPM reacts with catecholborane to form a spiroborate ester, which can be an efficient catalyst for the synthesis of enantiopure alcohols by borane reduction of acetophenone.[2]The catalyst generated in situ by reacting DPPM with borane-diethylaniline, can efficiently catalyze the enantioselective reduction of 2′-fluoroacetophenone.[3]Mesoporous SBA-15 silica functionalized with DPPM can catalyze the addition of diethylzinc to benzaldehyde to form (S)-1-phenyl-propanol.[4]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
200

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99%

form:
solid

optical activity:
[α]20/D −67°, c = 3 in chloroform

mp:
77-80 °C (lit.)

SMILES string:
OC([C@@H]1CCCN1)(c2ccccc2)c3ccccc3

InChI:
1S/C17H19NO/c19-17(16-12-7-13-18-16,14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16,18-19H,7,12-13H2/t16-/m0/s1

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OGCGXUGBDJGFFY-INIZCTEOSA-N

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1S/C8H16O4/c1-9-7(10-2)5-6-8(11-3)12-4/h5-8H,1-4H3/b6-5+

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ZFGVCDSFRAMNMT-AATRIKPKSA-N

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