77968
(R)-(+)-α-Methylbenzyl isocyanate
for chiral derivatization, LiChropur™, ≥99.0%
Manufacturer: Supelco
CAS Number: 33375-06-3
Synonym(S): (R)-(+)-1-Phenylethyl isocyanate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 ML | 77968-1-ML | In Stock | ₹ 14,670.00 |
| 5 ML | 77968-5-ML | In Stock | ₹ 61,140.00 |
77968 - 1 ML
In Stock
Quantity
1
Base Price: ₹ 14,670.00
GST (18%): ₹ 2,640.60
Total Price: ₹ 17,310.60
grade
for chiral derivatization
Quality Level
100
Assay
≥99.0% (sum of enantiomers, GC)≥99.0%
form
liquid
optical activity
[α]20/D +10.5±0.5°, neat
optical purity
enantiomeric ratio: ≥99.5:0.5 (GC)
quality
LiChropur™
technique(s)
HPLC: suitable
refractive index
n20/D 1.513 (lit.)n20/D 1.513
bp
55-56 °C/2.5 mmHg (lit.)
Description
- General description: (R)-(+)-a-Methylbenzyl isocyanate [(R)-(+)-MBIC] is a derivatizing agent.[1]
- Application: (R)-(+)-MBIC has been used in derivatization of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to form 4-(methylnitrosamino)-1-(a-methylbenzylcarbamoyl)-1-(3-pyridyl)butane. It has also been used in isolating hydroxyl acid, converting it to Methyl-4-[(S)-a-methylbenzylcarbamoyl]-4-(3-pyridyl)- butanoate which was further analysed by LC-MS/MS.1 It reacts with hydrate hydrochloride ketoaniline to yield hemiaminal, 3-((1R)-1-Phenylethyl)-(4S)-6-chloro-4-hydroxy-4-(trifluoromethyl)-1,3,4-trihydroquinazolin-2-one.[2]
- Other Notes: Reagent used for the determination of the enantiomeric purity of alcohols and amines[3][4][5][6]
- Recommended products: Discover LiChropur reagents ideal for HPLC or LC-MS analysis
- Legal Information: LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 2 Inhalation - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
closed cup
Flash Point(C)
closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
grade: for chiral derivatization
Quality Level: 100
Assay: ≥99.0% (sum of enantiomers, GC)≥99.0%
form: liquid
optical activity: [α]20/D +10.5±0.5°, neat
optical purity: enantiomeric ratio: ≥99.5:0.5 (GC)
quality: LiChropur™
technique(s): HPLC: suitable
refractive index: n20/D 1.513 (lit.)n20/D 1.513
bp: 55-56 °C/2.5 mmHg (lit.)
grade:
for chiral derivatization
Quality Level:
100
Assay:
≥99.0% (sum of enantiomers, GC)≥99.0%
form:
liquid
optical activity:
[α]20/D +10.5±0.5°, neat
optical purity:
enantiomeric ratio: ≥99.5:0.5 (GC)
quality:
LiChropur™
technique(s):
HPLC: suitable
refractive index:
n20/D 1.513 (lit.)n20/D 1.513
bp:
55-56 °C/2.5 mmHg (lit.)
grade: for chiral derivatization
Quality Level: 100
Assay: ≥99.0% (sum of enantiomers, GC)≥99.0%
form: liquid
optical activity: [α]20/D −10.5±0.5°, neat
optical purity: enantiomeric ratio: ≥99.5:0.5 (GC)
quality: LiChropur™
technique(s): HPLC: suitable
refractive index: n20/D 1.513n20/D 1.5145 (lit.)
bp: 55-56 °C/2.5 mmHg (lit.)
grade:
for chiral derivatization
Quality Level:
100
Assay:
≥99.0% (sum of enantiomers, GC)≥99.0%
form:
liquid
optical activity:
[α]20/D −10.5±0.5°, neat
optical purity:
enantiomeric ratio: ≥99.5:0.5 (GC)
quality:
LiChropur™
technique(s):
HPLC: suitable
refractive index:
n20/D 1.513n20/D 1.5145 (lit.)
bp:
55-56 °C/2.5 mmHg (lit.)
grade: Produced by Wacker Chemie AG, Burghausen, Germany, Life Science
Quality Level: 200
Assay: ≥98.0% cyclodextrin basis
form: powder
optical activity: [α]/D 154.0 to 156.0°
optical purity: __
quality: __
technique(s): __
refractive index: __
bp: __
grade:
Produced by Wacker Chemie AG, Burghausen, Germany, Life Science
Quality Level:
200
Assay:
≥98.0% cyclodextrin basis
form:
powder
optical activity:
[α]/D 154.0 to 156.0°
optical purity:
__
quality:
__
technique(s):
__
refractive index:
__
bp:
__
grade: __
Quality Level: 100
Assay: ≥95.0% (GC)95.0-105.0% (T)
form: liquid
optical activity: __
optical purity: __
quality: __
technique(s): __
refractive index: __
bp: __
grade:
__
Quality Level:
100
Assay:
≥95.0% (GC)95.0-105.0% (T)
form:
liquid
optical activity:
__
optical purity:
__
quality:
__
technique(s):
__
refractive index:
__
bp:
__